New publication: High-resolution
#methylome analysis uncovers stress-responsive genomic hotspots and drought-sensitive
#transposableelement superfamilies in the clonal Lombardy
#poplar.
https://doi.org/10.1093/jxb/erae262
High-resolution methylome analysis uncovers stress-responsive genomic hotspots and drought-sensitive transposable element superfamilies in the clonal Lombardy poplar
In poplar, different abiotic and biotic stresses induce methylation changes in common labile genomic regions, while drought induces global CHH hypermethyla
#AlternativeSplicing during development.
#scRNAseq of mouse
#oocyte to
#blastocyst reveals large-scale isoform switching &
#TransposableElement regulation during the maternal-to-zygotic gene transition
#PLOSBiology https://plos.io/4bBFFu1 
Single-cell analysis of isoform switching and transposable element expression during preimplantation embryonic development
Alternative splicing is an essential regulatory mechanism for development and pathogenesis. This study uses single cell sequencing of mouse oocyte to plastocyst to reveal large-scale of isoform switching and transposable element regulation during the maternal-to-zygotic gene transition.
From
@JohannConfais 📢 [JOB ALERT] : 1 an de CDD Ingénieur-e d'étude en développement logiciel INRAE URGI pour améliorer la portabilité et l’évolutivité de la suite logicielle
#REPET dans l'annotation des
#TransposableElement :
https://sfbi.fr/emplois/offre/202308020700-cdd-ingenieur-e-en-developpement-logiciel#Conda,
#Snakemake,
#SingularityIngénieur-e en développement logiciel | SFBI Société Française de Bioinformatique
Emploi en bioinformatique à Versailles CDD IE
Jumping Genes Can Cause Movement Disorder: Study
Mice with overactive LINE-1 retrotransposons in their brains exhibit movement difficulties, suggesting the genetic elements may play a role in ataxia in humans.
I never actually posted an #introduction toot, so here it is:
Doing #bioinformatics at Masaryk University #Brno, tooting about #science and life in general. PhD in #PlantBiology from UIUC. Interested in #G-quadruplexes, repetitive sequences (aka #transposons or #repeats) and #genome evolution.
#plants #repeat #dna #protein #PlantBiology #transposon #TransposableElement #Gquadruplex #rstats #linux
NIOO-KNAW
PLOS Biology
conda
Matej Lexa