Single-cell analysis of isoform switching and transposable element expression during preimplantation embryonic development

Alternative splicing is an essential regulatory mechanism for development and pathogenesis. This study uses single cell sequencing of mouse oocyte to plastocyst to reveal large-scale of isoform switching and transposable element regulation during the maternal-to-zygotic gene transition.

Yolk granule fusion and microtubule aster formation regulate cortical granule translocation and exocytosis in zebrafish oocytes

The localization and release of cortical granules at the oocyte surface constitutes a critical step in oocyte maturation in preventing polyspermy. This study shows that in zebrafish oocytes this process is driven by the concerted activities of yolk granule fusion and microtubule aster contraction.

83 Carotenoids presence in zona pellucida of human oocytes: potential role of chemical compounds evaluation by life-cell imaging for oocyte selection

Conservation of oocyte development in germline cysts from Drosophila to mouse

Early oocyte development takes place in germline cysts and is strikingly conserved from Drosophila to mouse, reflecting common mechanisms that may help reverse aging and specify oocyte and early embryo polarity.