The fungi living in the body play an important role in health – here’s what you should know about the ‘mycobiome’ | The-14

The body’s fungi, known as the mycobiome, affect gut, skin, and vaginal health. Imbalance can cause infections and disease—research is revealing its vital role.

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#Fungi in the gut #microbiome ( #mycobiome) are somewhat neglected. This study of gut fungal profiles across natural populations of humans & non-human primates, by @symbionticism &co, reveals significant fungal cospeciation patterns in #hominids @PLOSBiology https://plos.io/46LX4zD
What determines the human gut fungal community? Emily van Syoc, @erdavenport @symbionticism &co present the first #GWAS of human genetic loci that influence the relative abundance of gut #fungi, linking these to disease risk #mycobiome @PLOSBiology https://plos.io/42bCKou
"accounts for roughly 0.1% of the microbiome—a term that includes not only bacteria and fungi but also the archaea, viruses, and parasites that colonize our skin, gut, respiratory tract, and urogenital tract. While scientists have documented hundreds of fungal species in human guts, only a few dozen are common across individuals" https://www.nationalgeographic.com/premium/article/mycobiome-fungi-gut-health-microbiome re: #mycobiome #biofilm #dysbiosis et al. via #natgeo
How underground fungi shape forests

A large study involving 43 research plots in the Forest Global Earth Observatory (ForestGEO) Network—including a swath of trees at Tyson Research Center, the environmental field station of Washington University in St. Louis—has helped clarify the power of underground fungi to shape forests.

Phys.org

Interesting mini review discussing the strengths & limitations of the use of ITS region for fungal metabarcoding.

The amplicon sequence variant terminology comes for some criticism. 😅

#mycobiome #microbiome

https://www.sciencedirect.com/science/article/pii/S175450482300051X

Debunked: Study Finds No Connection Between Common Fungus and Pancreatic Cancer
Duke Health researchers, working to validate a four-year-old theory that a common fungus might trigger pancreatic cancer, have found no such link. Despite the initial promise, their comprehensive analysis did not support an association between fungi and the development of pancreatic cancer.
https://scitechdaily.com/debunked-study-finds-no-connection-between-common-fungus-and-pancreatic-cancer/?expand_article=1 #fungus #pancreatic #cancer #debunk #intrinsic #mycobiome
Debunked: Study Finds No Connection Between Common Fungus and Pancreatic Cancer

A study conducted four years ago suggested a potential link between a common type of fungus and the development of pancreatic cancer, providing a promising new view of the deadly disease. However, upon attempting to confirm this discovery, researchers from Duke Health found no such connection. Th

SciTechDaily
@Rhyothemis FWIW, there's currently some hot debate over the validity of some of these "#mycobiome" associations with #cancer Not related to the Cell paper you referenced, but a high-profile one nevertheless: https://www.nature.com/articles/s41586-023-06292-1
Revisiting the intrinsic mycobiome in pancreatic cancer - Nature

Nature
More than 6 million data points prove the influence of climate on global fungal occurrence

A new study by Bayreuth scientists has shown that temperature has a significant influence on the timing and duration of fungal fruiting in key areas of the world. The research results were published in the journal Ecology Letters and shed new light on the global impact of climate change on occurrences of fungi in nature.

Phys.org
Having IMPACTT 2023 Symposium - IMPACTT microbiome

Join us July 10-12, 2023 in Canmore, AB, Canada for an in-person symposium dedicated to microbiome research.

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