Sharing the best of humanity with the world, one story at a time.Research definitely claims going to bed exactly at 10pm is the ideal for better sleep
https://fed.brid.gy/r/https://www.upworthy.com/research-says-go-to-bed-at-10
UberZeitgeistSnorer versus Snored
Bedroom battle nightly waged
Snorer always wins
#Haiku #OneHaikuADay #WritersCollective #writingcommunity #BackToHaiku #Sleep #Bed #Bedroom #Snore #Snoring #Snorer #Snored #Sleep #Sleeping #Battle #2026 #Photography
January 19, 2026
Jesse IsraelSleeping Less? Your Blood Pressure is Rising #health #sleep #bloodpressure
Many people underestimate the importance of sleep for overall health. Did you know that lack of sleep can lead to high blood pressure? Sleep plays a crucial role in heart health, but many adults struggle to get enough rest. In the US, over 70 million adults are sleepdeprived. This sleep deprivation correlates with high blood pressure affecting around 75 million people worldwide.
Jesse IsraelSleeping Less? Your Blood Pressure is Rising #health #sleep #bloodpressure https://jandjinvestllc.com/sleeping-less-your-blood-pressure-is-rising-health-sleep-bloodpressure-2/
Sleeping Less? Your Blood Pressure is Rising #health #sleep #bloodpressure
Many people underestimate the importance of sleep for overall health. Did you know that lack of sleep can lead to high blood pressure? Sleep plays a crucial role in heart health, but many adults struggle to get enough rest. In the US, over 70 million adults are sleepdeprived. This sleep deprivation correlates with high blood pressure affecting around 75 million people worldwide.
Sleeping Less? Your Blood Pressure is Rising #health #sleep #bloodpressure https://jandjinvestllc.com/sleeping-less-your-blood-pressure-is-rising-health-sleep-bloodpressure/
Metro – Metro.co.uk: News, Sport, Showbiz, Celebrities from MetroThis space-saving Dunelm bed made my bedroom feel like a luxury hotel – and it’s on sale
flypapers📰 "Stuxnet balances mitochondria homeostasis by regulating uhg5 and parkin"
https://doi.org/doi:10.1016/j.celrep.2025.116855
https://pubmed.ncbi.nlm.nih.gov/41548216/
#Mitochondria #Drosophila #Sleep
https://doi.org/doi:10.1016/j.celrep.2025.116855
https://pubmed.ncbi.nlm.nih.gov/41548216/
#Mitochondria #Drosophila #Sleep
📰 "Shaker potassium channel mediates an age-sensitive neurocardiac axis regulating sleep and cardiac function in Drosophila"
https://doi.org/doi:10.1007/s10522-026-10386-4
https://pubmed.ncbi.nlm.nih.gov/41548155/
#DrosophilaMelanogaster
#Circadian
#Drosophila #Sleep
https://doi.org/doi:10.1007/s10522-026-10386-4
https://pubmed.ncbi.nlm.nih.gov/41548155/
#DrosophilaMelanogaster
#Circadian
#Drosophila #Sleep
Shaker potassium channel mediates an age-sensitive neurocardiac axis regulating sleep and cardiac function in Drosophila - Biogerontology
The Shaker (Sh) gene in Drosophila melanogaster encodes a voltage-gated potassium channel that regulates neuronal excitability and is well known for its role in sleep regulation; however, its contribution to cardiac physiology and neurocardiac communication remains insufficiently explored. In this study, we investigated how two Sh-mutations (Shmns and Sh5) influence heart function and sleep/circadian behaviors to identify potential age-dependent neurocardiac interactions. Cardiac performance and sleep/activity were examined across aging cohorts under normal conditions, circadian disruption, and with or without time-restricted feeding (TRF). Shmns mutants exhibited progressive cardiac decline with age, including increased heart period, elevated arrhythmicity, extended systolic and diastolic intervals, reduced contraction rate, and overall impaired cardiac output, along with disorganization of actin-rich myofibrils. These defects paralleled severe sleep loss and hyperactivity, suggesting a tight link between sleep/circadian dysregulation and cardiac impairment. Circadian misalignment further worsened both behavioral and cardiac deficits, whereas TRF partially improved select abnormalities, indicating feeding-time modulation of Sh-related phenotypes. Tissue-specific knockdown of Sh in cardiac and neuronal tissues recapitulated key mutant features, and notably, neuronal knockdown alone impaired cardiac behavior, supporting a functional neurocardiac regulatory axis mediated by Shaker-dependent electrical signaling. Together, these results demonstrate that Shaker channels contribute to an age-sensitive interplay between sleep/circadian regulation and cardiac homeostasis in Drosophila. Although direct extrapolation is limited, parallels with KCNA1-associated cardiac and neuronal abnormalities in humans suggest conserved Kv channel functions in neurocardiac dysfunction. Overall, this study identifies Shaker as a critical mediator of aging-, feeding-, and circadian-sensitive cross-tissue regulation of cardiac function, providing broader insight into mechanisms underlying neurocardiac communication. Our study establishes Shaker as a critical mediator of aging, circadian-sensitive, cross-tissue physiological regulation of cardiac function. Graphical abstract Highlights the role of the Shaker (Sh) potassium channel in linking neuronal and cardiac function in Drosophila. Shmns (Mini sleep) mutations cause age-dependent cardiac dysfunction and severe sleep loss (doted black head arrow). Circadian disruption worsens these effects, while time-restricted feeding (TRF) partially rescuing them (doted green blunt head arrow). Neuronal-specific Sh knockdown impairs heart function, revealing a neurocardiac axis critical for sleep and cardiac homeostasis.
Justin Farrimond