getmischFeb 28
100 years on Restaurant Row, Barbetta is closing after owner passed last month, at 93. FAB PICS of decor, garden seating, famous customers. They bought FOUR brownstones in a row from the Astors in 1925, wow.
#NYC #midtown #Manhattan #RestaurantRow #NewYorkCity #Italian #restaurant #Barbetta #closing #imported #chandeliers & #truffles #Madonna #DudleyMoore #DustinHoffman #LizTaylor #Broadway https://www.diningandcooking.com/2534273/manhattans-oldest-italian-restaurant-to-close-after-120-years-remarkable-journey-2/
Manhattan’s oldest Italian restaurant to close after 120 years: ‘Remarkable journey’ - Dining and Cooking

Barbetta closing

Dining and Cooking
Dining and CookingJan 22

Laura Maioglio, Longtime Owner of Barbetta on Restaurant Row, Has Died

Laura Maioglio — the force of taste, tradition and meticulous hospitality behind Barbetta, the storied Italian landmark on W46th Street — has died, the restaurant announced Wednesday evening. Laur…
#dining #cooking #diet #food #Italiancuisine #Italia #Italian #italiancuisine #italiano #italy #OBITUARY #restaurantrow
https://www.diningandcooking.com/2479539/laura-maioglio-longtime-owner-of-barbetta-on-restaurant-row-has-died/

Mediterranean DietOct 8

Pulpería Latin Mediterranean Kitchen: A ritual of flavor on Restaurant Row

Pulpería Latin Mediterranean Kitchen’s Aegan Trout Tartare. Photo courtesy of Pulpería Latin Mediter…
#dining #cooking #diet #food #mediterranean #MediterraneanDiet #MediterraneanFood #margarita #Mediterranean #mediterraneanfood #pulperu00eda #pulperu00edalatinmediterraneankitchen #restaurant #restaurantrow
https://www.diningandcooking.com/2322717/pulperia-latin-mediterranean-kitchen-a-ritual-of-flavor-on-restaurant-row/

Dining and CookingOct 8

Pulpería Latin Mediterranean Kitchen: A ritual of flavor on Restaurant Row

Pulpería Latin Mediterranean Kitchen’s Aegan Trout Tartare. Photo courtesy of Pulpería Latin Mediterranean Kitchen I am a woman from D…
#dining #cooking #diet #food #MediterraneanFood #margarita #Mediterranean #mediterraneanfood #pulperu00eda #pulperu00edalatinmediterraneankitchen #restaurant #restaurantrow
https://www.diningandcooking.com/2322717/pulperia-latin-mediterranean-kitchen-a-ritual-of-flavor-on-restaurant-row/

Redish LabJul 30, 2025

We're still doing science!

Kocharian, A., Redish, A.D. & Rothwell, P.E. Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind. Nature Neuroscience (2025).

https://www.nature.com/articles/s41593-025-02015-z

One of many exciting results: When mice change their mind about a choice (quitting out of the wait zone on our #RestaurantRow task), there is a dip in dopamine, even though there is no new information provided. Creating such a dip with optogenetic inhibition increases the likelihood of quitting.

#neuroscience

Also available as a preprint on biorxiv. https://www.biorxiv.org/content/10.1101/2024.09.16.613237v1

Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind - Nature Neuroscience

Differences in neuroeconomic decision-making influence nucleus accumbens dopamine dynamics and reflect choice confidence during evaluation, as well as past and future value during re-evaluation, which can causally lead to change-of-mind behaviors.

Nature
Show threadRedish LabJul 18, 2025

@elduvelle_neuro @Andrewpapale
@BrianMSweis

#CrossSpecies #neuroscience

As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.

Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.

Sunk cost sensitivity during change-of-mind decisions is informed by both the spent and remaining costs - Communications Biology

Computationally parallel ‘change-of-mind’ tasks in mice, rats and humans are analysed and demonstrate that sensitivity to sunk costs during re-evaluation depends on the awareness of time spent and remaining.

Nature
Show threadRedish LabDec 8, 2024

@elduvelle_neuro

Yes, the effect of reward on replay is more nuanced. There are changes in rate across the waiting period and one needs to take into account these changes to see effects.

My memory is that the Ambrose paper only looked at rewarded vs non-reward, which doesn't get at the real issue (which is value and changes in value).

Take a look at B. Schmidt, A. D. Redish (2021) “Disrupting the medial prefrontal cortex with DREADDs alters hippocampal sharp-wave ripples and their associated cognitive processes” Hippocampus. 31(10):1051-1067.https://onlinelibrary.wiley.com/doi/10.1002/hipo.23367 for a more nuanced story.

#hippocampus #replay #neuroscience
#RestaurantRow