Mastodawn

Redish Lab Jul 18, 2025

@elduvelle_neuro @Andrewpapale
@BrianMSweis

As Andy Papale said, we have a bunch of papers with both rats and mice on the #RestaurantRow task. (The data is all in https://www.nature.com/articles/s42003-022-04235-6, and publicly available.) Generally, we talk about similarities, but mice learn slower. Rats show the transition from wait zone to #precommitment in the offer zone in a few days, while mice take a lot longer.

Another space where I think there have been rat and mouse comparisons (although I don't find any explicit comparisons) is in the place field stability literature. My memory is that Cliff Kentros had really cool data on (#PlaceCell) #PlaceField stability as a function of #hippocampus #dopamine levels and task. (https://www.nature.com/articles/s42003-022-04235-6) Rats tended to live on the high-DA (place cells are stable) side while mice tended to live on the low-DA (place cells are unstable) side. But both could be manipulated with tasks and #dopamine (ant)agonists. I don't know if anyone explicitly looked at this.

Sunk cost sensitivity during change-of-mind decisions is informed by both the spent and remaining costs - Communications Biology

Computationally parallel ‘change-of-mind’ tasks in mice, rats and humans are analysed and demonstrate that sensitivity to sunk costs during re-evaluation depends on the awareness of time spent and remaining.

Nature

El Duvelle Neuro Jan 16, 2024

Please welcome the great @aheadofthenerve to Mastodon / the Fediverse! So nice to have another #PlaceCell #Neuroscientist on here 😁 (and also a #CalciumImaging expert)!

#Hippocampus #NeuroRats

From: @aheadofthenerve
https://neuromatch.social/@aheadofthenerve/111767478048631695

(((Dr Hannah Wirtshafter))) 🔬 (@[email protected])

I guess we do #introduction posts over here? I work on the #neuroscience (am I doing those hashtags right!?) of learning and memory, specifically how we learn while we navigate space and context. To do this, I take in vivo recordings (currently calcium imaging but ephys has my heart) of freely moving rats! After that, I use computational and mathematical approaches to analyze their neural activity! I am currently a BRAIN Initiative K99/R00 postdoc at Northwestern working with John Disterhoft and Sara Solla. I was trained at MIT with Matt Wilson, where I got my PhD in biology, and my BS is from Carnegie Mellon. Welcome!

Neuromatch Social

Show thread

El Duvelle Neuro Sep 11, 2023

6 - A thread of part II of our #4Room #PlaceCell paper, explaining how they create different representations for each of our 4 geometrically-identical rooms:
https://elduvelle.github.io/ElDuvelle/status/1319674602658746369/

Same paper as this post

This was a little surprising because many studies show that identical geometry is usually sufficient to generate very similar place cell maps (e.g . Place field repetition and spatial learning in a multicompartment environment)
The differences could be due to the different directional signal when entering each different room...

6/x

El Duvelle 🌍 on Twitter (archived)

Place cell activity in a 4-room environment --PART II🎬--How do place cells represent complex, multicompartmented spaces?🤔Preprint (same as for place cells and connectivity): https://www.biorxiv.org/content/10.1101/2020.10.20.346130v1.article-metricsThread: 🔽1/

El Duvelle Neuro Sep 11, 2023

Here are a few of my favourites from my twitter-detached archive :

1- Types of #PlaceCell papers...

https://elduvelle.github.io/ElDuvelle/status/1388075267453857792/

#Neuroscience #Neuroscientist #Hippocampus #NeuroPapers

1/x

El Duvelle 🌍 on Twitter (archived)

My contribution: #PlaceCell papers😅 (Hoping that this hasn't been done yet...) https://twitter.com/UriCohen42/status/1387652186037960706

Raphael_Brito Jul 28, 2023

I guess it's time to finelly do my #introduction !
I'm a PhD student in Michaël Zugaro's lab
I'm studying the interaction between spatial coding in the #hippocampus and reward representation by #dopamine signaling, especially the VTA - Nucleus Accumbens pathway.
Doing ephys extra-cellular recordings in freely mooving rats trying to catch some chocolate milk!
The dying bird convinced me that mastodon was the way to go and I'm glad to see the neuroscience community growing!

I'm a bit shy on social media but I'll boost everything related to the brain that I find interesting 🧠
#PlaceCell #neuroscience #reward

El Duvelle Apr 16, 2023

Very early sneak peek on what I'm currently working on... Yes it's #PlaceCell #Replay !!

#Hippocampus #Hexamaze

El Duvelle Mar 26, 2023

fun #PaperQuote, from the methods of a #PlaceCell paper:

[…] small white Christmas tree lights, centered 160 cm over the
cylinder floor, provided the only illumination in the black room. These conditions provided very little directional information other than the cue card; even the experimenters at times became disoriented after some time in the room, opening the curtain at the wrong location at the end of the session when trying to find the door.

… ooops 😂
The paper: Knierim et al., 1995

(discovered by Roddy Grieves, not on Mastodon)

Place cells, head direction cells, and the learning of landmark stability

Previous studies have shown that hippocampal place fields are controlled by the salient sensory cues in the environment, in that rotation of the cues causes an equal rotation of the place fields. We trained rats to forage for food pellets in a gray cylinder with a single salient directional cue, a white card covering 90 degrees of the cylinder wall. Half of the rats were disoriented before being placed in the cylinder, in order to disrupt their internal sense of direction. The other half were not disoriented before being placed in the cylinder; for these rats, there was presumably a consistent relationship between the cue card and their internal direction sense. We subsequently recorded hippocampal place cells and thalamic head direction cells from both groups of rats as they moved in the cylinder; between some sessions the cylinder and cue card were rotated to a new direction. All rats were disoriented before recording. Under these conditions, the cue card had much weaker control over the place fields and head direction cells in the rats that had been disoriented during training than in the rats that had not been disoriented. For the former group, the place fields often rotated relative to the cue card or completely changed their firing properties between sessions. In all recording sessions, the head direction cells and place cells were strongly coupled. It appears that the strength of cue control over place cells and head direction cells depends on the rat's learned perception of the stability of the cues.

Journal of Neuroscience

El Duvelle Mar 20, 2023

Here are some #PlaceCell clusters for you (#Tetrode recordings) 😃
#Hippocampus