트라우마 증상과 영향, 최신 뇌과학 자가 극복 방법

https://habitdays.com/posts/4037

Luz-Ardiden - Luz-Saint-Sauveur - Hautes-Pyrénées - France

#npy #destinationpyrenees #tourismeoccitanie #npyski #hautespyrenees #pyrenees #francemontagnes #montain #montainlovers #france #snow #beautifuldestinations #landscape #country #LuzSaintSauveur #photography

Pyrénées - France

#npy #destinationpyrenees #tourismeoccitanie #npyski #hautespyrenees #pyrenees #francemontagnes #montain #montainlovers #france #snow #beautifuldestinations #minimal #minimalism #minimalist #France #photography

Happy & proud to share our latest work with the #bluespot community, #locuscoeruleus enthusiasts, and anyone else willing to read 😉

https://www.biorxiv.org/content/10.1101/2023.10.16.562534v1

4 years ago, we had the idea that endogenous neuromodulatory systems are in place that control LC activity, thereby promoting adaptive behavioral responses in challenging environments.

We examined the role of Neuropeptide Y, as a possible candidate system for this, and identified a new population of #NPY-expressing neurons, distributed in the pericoerulean space.

We showed that peri-LC NPY cells innervate the region, providing #NPY input onto #noradrenergic neurons of the LC, and strongly inhibiting their activity, via Y1Rs.

Next, we showed that chemogenetic stimulation of NPY cells led to anxiety-relief, via Y1Rs, and conversely, inhibition of NPY neurons triggered an anxiogenic phenotype.

Together, we showed a novel role for NPY-mediated #neuromodulation of the LC in adaptive behaviors.

We re happy to hear your thoughts /ideas /feedback on our data.

Please share/boost. Happy reading 🔵

#preprint #neuroscience #systemsneuro #ephys #stress