The Latest From RepRapMicron – Nail Gel, First Objects, And More

We’ve been following [Vik Olliver]’s progress on the μRepRap project with interest for some time now. The project’s goal is to build a 3D printer that can print feature sizes down to about 10 micro…

Hackaday

Teach your #microscope how to print: Low-cost rapid-iteration #OpenSource #microfabrication for #biology:

- no cleanroom required
- replace SU-8 #photoresist & silicon wafers by #3Dprinting #resin & microscope slides
- #fluorescence microscope-based maskless #photolithography
- achieve µm-scale precision across cm-sized areas

https://doi.org/10.1039/D5LC00181A
#DIYbio #lab #instruments #microfluidics

Teach your #microscope how to print: Low-cost & rapid-iteration #OpenSource #microfabrication for #biology:

-µm-scale precision across cm-sized areas
-no cleanroom requirement
-SU8 replacement

Preprint: https://doi.org/10.1101/2025.02.20.639256
GitHub: https://github.com/hinderling/fabscope
#DIYbio #lab #instuments #imaging #microfluidics #fabrication #3Dprinted

Teach your microscope how to print: Low-cost and rapid-iteration microfabrication for biology

The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an accessible microfabrication workflow that addresses these challenges by integrating consumer 3D printing techniques and repurposing standard fluorescence microscopes equipped with DMDs for maskless photolithography. Our method achieves micrometer-scale precision across centimeter-sized areas without clean room infrastructure, using affordable and readily available consumables. We demonstrate the versatility of this approach through four biological applications: inducing cytoskeletal protrusions via 1 μm-resolution surface topographies; micropatterning to standardize cell and tissue morphology; fabricating multilayer microfluidic devices for confined cell migration studies; imprinting agar chambers for long-time tracking of C. elegans . Our protocol drastically reduces material costs compared to conventional methods and enables design-to-device turnaround within a day. By leveraging open-source microscope control software and existing lab equipment, our workflow lowers the entry barrier to micro-fabrication, enabling labs to prototype custom solutions for diverse experimental needs while maintaining compatibility with soft lithography and downstream biological assays. ### Competing Interest Statement The authors have declared no competing interest.

bioRxiv
Postdoc - Acoustofluidic Platforms for Automated Sorting of Synthetic Cells

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Up Close And Personal With A MEMS Microphone

If you’ve ever wondered what lies beneath the barely visible hole in the can of a MEMS microphone, you’re in luck, because [Zach Tong] has a $10 pair of earbuds to sacrifice for the cau…

Hackaday

Been working on some electrode patterns, starting to get some nice results. 🥳

Edges are a bit fuzzy/burry since I'm sputter depositing rather than something more line-of-sight like thermal evap. Getting a better dep method is high on the todo list.

Resist stack is an MMA/PMMA bilayer, substrate is silicon + ~100nm CuO, and electrodes are 150nm of aluminum via lift-off.

In theory, these should act as metal-semiconductor-metal photodetectors. Unsure if my test gear is sufficient though, might need to upgrade my electronics a bit. We'll see! 🤞

#microfabrication #microscopy #electronmicroscopy #SEM

This method offers the potential to revolutionize #electronics, #optics, and beyond. #nanoimprint #Microfabrication #NIL

RT @uni_lu: 📣 #uni_lu researcher receives the first European Innovation Council (@EUeic) grant in Luxembourg for the REMAP project which aims to make #microfabrication sustainable.

#Sustainability
@unige_en @CNRS @NCSR_Demokritos @RINA1861
https://wwwen.uni.lu/university/news/slideshow/university_researcher_receives_the_first_eic_grant_in_luxembourg

🐦🔗: https://nitter.eu/EUeic/status/1522237058043023363

University researcher receives the first EIC grant in Luxembourg

A consortium including the University of Luxembourg has been awarded a prestigious PathFinder Open grant of the European Innovation Council (EIC) that ...

University of Luxembourg

Getting a Fly’s-Eye View with Microfabricated Lens Arrays

Atomic force microscopy, laser ablation, and etching with a witches brew of toxic chemicals: sounds like [Zachary Tong] has been playing in the lab again, and this time he found a way to fabricate arrays of microscopic lenses as a result.

Like many of the best projects, [Zach]'s journey into micro-fabrication started with a happy accident. It happened while he was working on metal-activated chemical etching (MACE), which uses a noble metal catalyst to selectively carve high-aspect-ratio features in silicon. After blasting at a silver-coated silicon wafer with a laser, he noticed the ablation pits were very smooth and uniform after etching. This led him to several hypotheses about what was going on, all of which he was able to test.

The experiments themselves are pretty interesting, but what's really cool is that [Zach] realized the smooth hemispherical pits in the silicon could act as a mold for an array of microscopic convex lenses. He was able to deposit a small amount of clear silicone resin into the mold by spin-coating, and (eventually) transfer the microlens array to a glass slide. The lenses are impressively small -- hundreds of them over only a couple hundred square microns -- and pretty well-formed. There's always room for improvement, of course, but for an initial attempt based on a serendipitous finding, we'd call it a win. As for what good these lenses are, your guess is as good as ours. But novel processes like these tend to find a way to be useful, and the fact that this is coming out of a home lab doesn't change that fact.

We find this kind of micro-fabrication fascinating. Whether it's making OLED displays, micro-machining glass with plasma, or even rolling your own semiconductors, we can't get enough of this stuff.

#parts #science #etching #hydrofluoricacid #mace #mems #metalassistecchemicaletching #microfabrication #molding #nitricacid #pdms #silcon #silcone #silicon

Getting A Fly’s-Eye View With Microfabricated Lens Arrays

Atomic force microscopy, laser ablation, and etching with a witches brew of toxic chemicals: sounds like [Zachary Tong] has been playing in the lab again, and this time he found a way to fabricate …

Hackaday