Hi floss.social. Just moved in from https://fosstodon.org/@ygor

I'm an #ElectricalEngineer from #Brazil, currently living in #France for many years. I work as a #SoftwareDeveloper, writing proprietary software for #microfluidics (I do wish I could work on #FreeSoftware for a living instead). My favorite programming language is #rustlang, but I use/have used about a dozen other languages, they're alright. I'm also a fan of #animation.

#introduction

ygor (@ygor@fosstodon.org)

245 Posts, 122 Following, 1 Follower · #ElectricalEngineer from #Brazil, working as a #SoftwareDeveloper in #France

Fosstodon

I guess I never introduced myself, so here goes:

I'm an #ElectricalEngineer from #Brazil, currently living in #France for many years. I work as a #SoftwareDeveloper, writing proprietary software for #microfluidics (I do wish I could work on #FreeSoftware for a living instead). My favorite programming language is #rustlang, but I use/have used about a dozen other languages, they're alright. I'm also a fan of #animation.

#introduction

Teach your #microscope how to print: Low-cost & rapid-iteration #OpenSource #microfabrication for #biology:

-µm-scale precision across cm-sized areas
-no cleanroom requirement
-SU8 replacement

Preprint: https://doi.org/10.1101/2025.02.20.639256
GitHub: https://github.com/hinderling/fabscope
#DIYbio #lab #instuments #imaging #microfluidics #fabrication #3Dprinted

Teach your microscope how to print: Low-cost and rapid-iteration microfabrication for biology

The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an accessible microfabrication workflow that addresses these challenges by integrating consumer 3D printing techniques and repurposing standard fluorescence microscopes equipped with DMDs for maskless photolithography. Our method achieves micrometer-scale precision across centimeter-sized areas without clean room infrastructure, using affordable and readily available consumables. We demonstrate the versatility of this approach through four biological applications: inducing cytoskeletal protrusions via 1 μm-resolution surface topographies; micropatterning to standardize cell and tissue morphology; fabricating multilayer microfluidic devices for confined cell migration studies; imprinting agar chambers for long-time tracking of C. elegans . Our protocol drastically reduces material costs compared to conventional methods and enables design-to-device turnaround within a day. By leveraging open-source microscope control software and existing lab equipment, our workflow lowers the entry barrier to micro-fabrication, enabling labs to prototype custom solutions for diverse experimental needs while maintaining compatibility with soft lithography and downstream biological assays. ### Competing Interest Statement The authors have declared no competing interest.

bioRxiv

Exciting News: I am thrilled to announce that our latest journal article‚ “Design and Characterization of a Magnetic Silicone Peristaltic Pump With Multiphysics Modeling” is now available via IEEE Xplore in IEEE/ASME Transactions on Mechatronics.

In this article, we report on the development of a magnetic peristaltic pump for #microfluidics, #bioengineering or #medicine that does not require rollers and thus reduces abrasion and mechanical stress.

Novel Magnetic Actuation Strategies for Precise Ferrofluid Marble Manipulation in Magnetic Digital Microfluidics: Position Control and Applications

Authors: Mohammad Hossein Sarkhosh, Mohammad Hassan Dabirzadeh, Mohamad Ali Bijarchi, Hossein Nejat Pishkenari

pre-print -> https://arxiv.org/abs/2412.02859

#robotics #control #manipulation #microfluidics

Novel Magnetic Actuation Strategies for Precise Ferrofluid Marble Manipulation in Magnetic Digital Microfluidics: Position Control and Applications

Precise manipulation of liquid marbles has significant potential in various applications such as lab-on-a-chip systems, drug delivery, and biotechnology and has been a challenge for researchers. Ferrofluid marble (FM) is a marble with a ferrofluid core that can easily be manipulated by a magnetic field. Although FMs have great potential for accurate positioning and manipulation, these marbles have not been precisely controlled in magnetic digital microfluidics, so far. In this study for the first time, a novel method of magnetic actuation is proposed using a pair of Helmholtz coils and permanent magnets. The governing equations for controlling the FM position are investigated, and it is shown that there are three different strategies for adjusting the applied magnetic force. Then, experiments are conducted to demonstrate the capability of the proposed method. To this aim, different magnetic setups are proposed for manipulating FMs. These setups are compared in terms of energy consumption and tracking ability across various frequencies. The study showcases several applications of precise FM position control, including controllable reciprocal positioning, simultaneous position control of two FMs, the transport of non-magnetic liquid marbles using the FMs, and sample extraction method from the liquid core of the FM.

arXiv.org
Postdoc - Acoustofluidic Platforms for Automated Sorting of Synthetic Cells

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv
Tiny laboratories that fit in your hand can rapidly identify pathogens using electricity https://buff.ly/4eT0IZg (Blanca H. Lapizco-Encinas, Rochester Institute of Technology) #microbiology #microfluidics #science
Tiny laboratories that fit in your hand can rapidly identify pathogens using electricity

Pathogens have distinct electrical charges, shapes and sizes. Measuring how quickly they move through an electric field can help researchers separate different species in a sample in minutes.

The Conversation
Together with the talented biophysicist Iana Kalinina, @AlyssaHudson83 also captured binding of the TG11 antibody to growing #Rhizopus arrhizus spores live in a #microfluidics chamber. #mucormycosis 9/ https://bit.ly/4eG3lyz
Characterization of the Spatiotemporal Localization of a Pan-Mucorales–Specific Antigen During Germination and Immunohistochemistry

A pan-Mucorales antibody binds to germinating hyphae and can discriminate Mucorales and Aspergillus hyphae by immunohistochemistry.

OUP Academic

#PRNTDpump: #OpenSource nonelectric spring-driven #syringe #pump with #3Dprinted components for #microfluidic applications:

-no external power requirement (off-grid usage)
-fabrication cost: $25-30

https://doi.org/10.1016/j.ohx.2024.e00550
#DIYbio #lab #instruments #microfluidics #FrugalScience

Open-source spring-driven syringe pump with 3D-printed components for microfluidic applications

The operation of microfluidic devices requires precise and constant fluid flow. Microfluidic systems in low-resource settings require a portable, inex…

An #OpenSource #DIY #Arduino benchtop device for highly scalable #millifluidic flow synthesis of #protein-based #nanoparticles:

-swift thermal formation (#STF) approach
-cost: $350

https://doi.org/10.1016/j.ohx.2024.e00554
#DIYbio #lab #instruments #nanotechnology #drugdelivery #microfluidics

A do-it-yourself benchtop device for highly scalable flow synthesis of protein-based nanoparticles

Synthesis of nanoparticles is typically carried out in batch procedures, which offer limited control of parameters, and a narrow range of possible bat…