Eli Roberson (he/him)

@thatdnaguy@genomic.social
487 Followers
416 Following
3.8K Posts

Using human genetics and genomics with applied bioinformatics to understand human disease. Just enough stats and server to make me dangerous with data. Well-marbled.

Lifetime achievement: Making an SRO tell me I might want to remove a grant review budget comment that a specific institutional charge rate was mob level extortion.

#Genetics #Genomics #RareVariants #DNASeq #RNASeq #SingleCell

#Inflammation #Hidradenitis #Arthritis #SystemicSclerosis #Autophagy

#rstats #python #SnakeMake

Lab website profilehttps://www.robersonlab.org/eli.html
FigSharehttps://figshare.com/authors/Elisha_Roberson/98532
GitHubhttps://github.com/eroberson
ORCIDhttps://orcid.org/0000-0001-5921-2399

i went to a medical appointment the other day

the doctor asked if he could use AI during the appointment

i said 'no'

he said i was the only one who had refused

pro tip: if what you say to AI is shared with an insurance company, if what you said is not what you said because AI made stuff up, if what you said is revealed in a breach

guess what, your insurance company will use that against you forever and ever

just say no to AI

#Academia #AcademicChatter #Genetics #Genomics

It's looking more and more like I'll end up missing #ASHG25 in Boston. I've been to every meeting (excepting digital covid meetings) since 2013.

University cost saving measures are moving toward blocking all professional travel allowances on the change of the fiscal year. 😕

Which would also be the first #ASHG that I've not live tooted since I started doing it. Times they are a changing.

Why? Because I'd edit and edit and edit. Then deploy on the cluster. Wait for run time. Then fail. Because the *rules* had a singularity command with the image. But I forgot to update the yaml file to include the new rules and image names.

In recent years, we pivoted away from bare metal installs and manually analyzing data files. Instead, we mostly use #Docker containers and #SnakeMake workflow management.

Our cluster runs containers. It's easy. Locally we use singularity. Also easy. But local servers use singularity defined in the rule. On cluster, a separate yaml is required to specify images...

Which means I've scripted scanning the SnakeMake files, pulling image and rule names, and writing the yaml automagically.

A+++ quote regarding mental illness and the LLM craze.

Eliezer Yudkowsky: “What does a human slowly going insane look like to a corporation? It looks like an additional monthly user.”

Unlocked article per @Nonilex

https://www.nytimes.com/2025/06/13/technology/chatgpt-ai-chatbots-conspiracies.html?unlocked_article_code=1.P08.q54v.5I9Hb7nYzpyW

They Asked ChatGPT Questions. The Answers Sent Them Spiraling.

Generative A.I. chatbots are going down conspiratorial rabbit holes and endorsing wild, mystical belief systems. For some people, conversations with the technology can deeply distort reality.

The New York Times

'Meredith,' some guys ask, 'why won't you shove AI into Signal?'

Because we love privacy, and we love you, and this shit is predictable and unacceptable. Use Signal ❤️

@hellomiakoda oof. That'd be a heck of a story. "Let's crack this open to see that's smudging the discs. It's since started overheating..."

Completely clogged with ant colony

California Cops Investigate ‘Immigration Protest’ With AI-Camera System | California cops are illegally sharing Flock automatic license plate reader (ALPR) data with other agencies out of state, who in turn are performing searches for ICE. https://www.byteseu.com/1120638/ #Technology
Just replaced a drive in my backup netbook and started it resilvering :-) Fortunately the hardest part (figuring out which drive was broken) was made trivial because one of the drives had an angry red LED on it.

#ZFS / #backups nerds - should I pause backups for 4 days while it resilvers or can I just let it go?
Pluralistic with a succinct reaction to the "catastrophically bad clause" being, apparently, pushed onto mastodon.social and at least suggested as a default from the source software of mastodon itself in a future update.
#mastodon #tos #meta #lawyers #privacy https://mamot.fr/@pluralistic/114706917718152039
Cory Doctorow (@pluralistic@mamot.fr)

And since mastodon.social is the flagship instance, which sets the moral example - and the workaday template - for most instances in the Fediverse, this catastrophically bad clause is likely to proliferate far and wide throughout the Fediverse, rendering most of this new, better internet unfit for use. Please, @Gargron@mastodon.social, reconsider this. It is a very bad look - and worse still, it's a very, very bad example.

Mamot - Le Mastodon de La Quadrature du Net
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California Cops Investigate ‘Immigration Protest’ With AI-Camera System | California cops are illegally sharing Flock automatic license plate reader (ALPR) data with other agencies out of state, who in turn are performing searches for ICE. https://www.byteseu.com/1120638/ #Technology