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A preprint highlights service run by the biological community and supported by The Company of Biologists.

https://prelights.biologists.com/

preLightshttps://prelights.biologists.com/

Improving anxiety research in rodents for a better understanding of human chronic ('trait') #anxiety.

Nándor Lipták covers a #preprint from the #MikicsLab combining behavioural tests with corticosterone measurements, #transcriptomics & #bioinformatics.

#preLight 👉 https://prelights.biologists.com/highlights/improving-anxiety-research-novel-approach-to-reveal-trait-anxiety-through-summary-measures-of-multiple-states/

Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states - preLights

Anxious rodents for the better understanding of human anxiety

preLights

Meet the #preLightsAmbassadors: Girish Kale.

Girish is currently a #postdoc #COSHeidelberg. He has represented #preLights at several national and international meetings already and is therefore a very natural Ambassador for the platform.

Interview: https://prelights.biologists.com/news/meet-the-prelights-ambassadors-girish-kale/

Meet the preLights Ambassadors: Girish Kale - preLights

In order to keep developing preLights and respond to the needs of the community, we recently launched the preLights Ambassador scheme. Four amazing preLighters have now been appointed as Ambassadors and we caught up with all of them to chat about the things that they’re excited to bring to this role during the coming year.[...] Read More

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When it comes to planarian stem cells, it's not a one-niche-fits-all situation.

First post as part of #preLightsPeerSupport, led by Girish Kale. Master’s student Rebecca Kern and Girish teamed up to cover a #preprint from the #Planaria1 lab!

Post 👉https://prelights.biologists.com/highlights/planarians-employ-diverse-and-dynamic-stem-cell-microenvironments-to-support-whole-body-regeneration/

Planarians employ diverse and dynamic stem cell microenvironments to support whole-body regeneration - preLights

When it comes to planarian stem cells, it's not a one-niche-fits-all situation.

preLights

Gaining ground in the development of Synthetic Mammalian Promoters.

#preLight from Jessica L Teo covering a #preprint from the #EnglishLab (led by Adam Zahm & William S Owens) that presents a toolkit of great value to the scientific #community!

Post 👉: https://prelights.biologists.com/highlights/discovery-and-validation-of-context-dependent-synthetic-mammalian-promoters/

Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters - preLights

Gaining ground in the development of Synthetic Mammalian Promoters

preLights

Meet the #preLightsAmbassadors: Martin Estermann.

Martin is currently a #postdoc #NIEHS and here we discuss the importance of being part of a #community that helps you connect to others, ask questions & build a network that you can rely on. 🌐

Interview: https://prelights.biologists.com/news/meet-the-prelights-ambassadors-martin-estermann/

Meet the preLights Ambassadors: Martin Estermann - preLights

In order to keep developing preLights and respond to the needs of the community, we recently launched the preLights Ambassador scheme. Four amazing preLighters have now been appointed as Ambassadors and we caught up with all of them to chat about the things that they’re excited to bring to this role during the coming year.[...] Read More

preLights

Fasten your actin belt!

Epithelial cells disassemble #caveolae to strengthen their cortical #cytoskeleton upon mechanical stress.

First #preLight from Teodora Piskova #RWTH covering a #preprint led by John Brooks (Yap Lab #IMBatUQ) & team.

preLight: https://prelights.biologists.com/highlights/caveola-mechanotransduction-reinforces-the-cortical-cytoskeleton-to-promote-epithelial-resilience-t20230615-1213/

Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience - preLights

Fasten your actin belt! Epithelial cells disassemble caveolae to strengthen their cortical cytoskeleton upon mechanical stress.

preLights

Tik-Tok of the Methylation clock: does DNA #methylation impact on our #lifespan?⏰

New #preLight post prepared by Jennifer Ann Black which covers a #preprint from Samuel Crofts, Eric Latorre-Crespo &Tamir Chandra.

#genetics #ageing #Mammals

#preLight: https://prelights.biologists.com/highlights/dna-methylation-rates-scale-with-maximum-lifespan-across-mammals-t20230614-1322/

DNA methylation rates scale with maximum lifespan across mammals - preLights

Tik-Tok of the Methylation clock: does DNA methylation impact on our lifespan?

preLights

How to use your neighbours to get ahead: #glioblastoma cells use #ExtracellularVesicles to encourage neighbouring #astrocytes to secrete pro-invasive #ECM components.

#preLight from Jade Chan covering work led by Dominik Koessinger #CRUK_BI

#CancerBiology

preLight: https://prelights.biologists.com/highlights/glioblastoma-extracellular-vesicles-influence-glial-cell-hyaluronic-acid-deposition-to-promote-invasiveness/

Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness - preLights

How to use your neighbours to get ahead: brain tumour cells use extracellular vesicles to encourage neighbouring astrocytes to secrete pro-invasive extracellular matrix components.

preLights

Divide et Impera.

Thanks to U-ExM, cheap and high resolution #imaging maps the asexual #reproduction cycle of #malaria parasites in red blood cells.

Latest #preLight from Nadja Hümpfer:

https://prelights.biologists.com/highlights/atlas-of-plasmodium-falciparum-intraerythrocytic-development-using-expansion-microscopy/

Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy - preLights

Divide et Impera. Thanks to U-ExM, cheap and high resolution imaging maps the asexual reproduction cycle of malaria parasites in red blood cells

preLights

Meet the #preLightsAmbassadors: Jennifer Ann Black

Jennifer is currently a #postdoc #usponline and tells us more about her plans for the coming year - one of which is to help strengthen the #ECR community in #Brazil 💪

Interview: https://prelights.biologists.com/news/meet-the-prelights-ambassadors-jennifer-ann-black/

Meet the preLights Ambassadors: Jennifer Ann Black - preLights

In order to keep developing preLights and respond to the needs of the community, we recently launched the preLights ambassador scheme. Four wonderful preLighters have now been appointed as Ambassadors and we caught up with all of them to chat about the things that they’re excited to bring to this role during the coming year.[...] Read More

preLights