Rxiv cytoskeleton3d ago
📰 "ARHGAP44 gene: a cytoskeleton mobility-related modulator with implications in pan-cancer prognostic risk and immune regulation"
https://doi.org/doi:10.3389/fonc.2026.1721943
https://pubmed.ncbi.nlm.nih.gov/41988127/
#Cytoskeleton
Frontiers | ARHGAP44 gene: a cytoskeleton mobility-related modulator with implications in pan-cancer prognostic risk and immune regulation

IntroductionRho GTPases have been a well-known family of small G proteins that regulate cellular cytoskeleton dynamics and are involved in multiple critical ...

Frontiers
Rxiv cytoskeleton4d ago
📰 "Beads, springs and fields: particle-based vs continuum models in cell biophysics"
https://arxiv.org/abs/2604.13827
#Physics.Comp-Ph #Physics.Bio-Ph #Cond-Mat.Soft #Cytoskeleton
Beads, springs and fields: particle-based vs continuum models in cell biophysics

Quantitative modeling has become an essential tool in modern biophysics, driven by advances in both experimental techniques and theoretical frameworks. Powerful high-resolution techniques now provide detailed datasets spanning molecular to tissue scales, allowing to visualize cellular structures with unprecedented detail. In parallel, developments in soft and active matter physics have established a robust theoretical basis for describing biological systems. In this context, two main modeling paradigms have emerged: particle-based models, which explicitly represent discrete components and their interactions, and continuum models, which describe systems through spatially varying fields. We compare these approaches across biological scales, highlighting their respective strengths, limitations, and domains of applicability. To keep our discussion biologically relevant, we focus on five systems of fundamental importance: the cytoskeleton, membranes, chromatin, biomolecular condensates and tissues. With this Review, we thus aim to provide a framework for both theorists and experimentalists to select appropriate modeling strategies, and highlight future directions in biophysical modeling.

arXiv.org
Rxiv cytoskeleton4d ago
📰 "Tetrahydrocurcumin Suppresses Bladder Carcinogenesis via Reprogramming O-GlcNAcylation-Phosphorylation Crosstalk"
https://www.biorxiv.org/content/10.64898/2026.04.12.717994v1?rss=1
#Cytoskeleton
Rxiv cytoskeleton4d ago
📰 "The cytoskeleton of pathogenic protists"
https://doi.org/doi:10.1042/BSR20254047
https://pubmed.ncbi.nlm.nih.gov/41983703/
#Cytoskeleton
The cytoskeleton of pathogenic protists

Abstract. The cytoskeleton is a key component of eukaryotic cells, including protists. It is composed of microtubules, microfilaments, and intermediate filaments. Here, we review the available information on the cytoskeleton of several relevant pathogenic protists, including Trypanosomatidae, Apicomplexa, Trichomonadidae, Giardia intestinalis, and Entamoeba histolytica. In protists, the first two components, made of tubulins and actin, predominate. Usually, they associate with each other and with other components to form complex structures. Emphasis is given to the following structures: flagellum, flagellar-cell body adhesion zone, paraflagellar rod, sub-pellicular microtubules, cytostome, conoid, adhesive disc, funis, median body, costa, axostyle, parabasal filaments, and clockwise filaments. On the other hand, filamentous structures made of not yet completely characterized proteins form structures such as the costa. Each structure is analyzed using morphological information obtained through modern microscopy techniques and biochemical data.

Portland Press
Rxiv cytoskeleton5d ago
📰 "Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons"
https://doi.org/doi:10.1126/scisignal.adx6752
https://pubmed.ncbi.nlm.nih.gov/41980068/
#Cytoskeleton
Rxiv cytoskeleton5d ago
📰 "Tau-Mediated Cytoskeletal Stabilization Modulates Cell Mechanics and Vulnerability to Mechanical Strain"
https://www.biorxiv.org/content/10.64898/2026.04.10.717705v1?rss=1
#Cytoskeleton
Rxiv cytoskeleton5d ago
📰 "Evolutionary principles underlying neuron subtype encoding and diversification in animals"
https://www.biorxiv.org/content/10.64898/2026.04.13.718258v1?rss=1
#Cytoskeleton
Rxiv cytoskeleton5d ago
📰 "Histidine phosphorylation of NME1 regulates the Hippo pathway via the ARHGAP17-CDC42-cytoskeleton axis"
https://doi.org/doi:10.1093/lifemedi/lnag002
https://pubmed.ncbi.nlm.nih.gov/41978798/
#Cytoskeleton
Histidine phosphorylation of NME1 regulates the Hippo pathway via the ARHGAP17–CDC42–cytoskeleton axis

Abstract. NME1 is a key metastasis suppressor whose activity depends on histidine phosphorylation, yet the biological significance of this modification rem

OUP Academic
Rxiv cytoskeleton6d ago
📰 "Dependence of ATP content in the formation of protrusions in DMPC GUVs under an AC electric field"
https://doi.org/doi:10.1140/epje/s10189-026-00581-z
https://pubmed.ncbi.nlm.nih.gov/41973276/
#Cytoskeleton
Rxiv cytoskeleton6d ago
📰 "Mechanical communication and function regulation of immune cells"
https://doi.org/doi:10.1016/j.fmre.2024.04.008
https://pubmed.ncbi.nlm.nih.gov/41971825/
#Cytoskeleton