Oliver Barnstedt

@[email protected]
351 Followers
264 Following
36 Posts
Neuroscientist at European Neuroscience Institute Göttingen. Group leader researching the neuronal circuitry underlying memory and action. Alumnus Jacobs University, Oxford, DZNE, LIN, OvGU.
Scholarhttps://scholar.google.com/citations?user=YArxXYgAAAAJ
ORCIDhttps://orcid.org/0000-0001-7924-6043
Githubhttps://github.com/obarnstedt
Twitterhttps://twitter.com/obarnstedt
Websitehttps://www.barnstedtlab.com
Oliver BarnstedtDec 6, 2024
🥳 BIG NEWS for the lab! 🥳 I'm excited to join the Göttingen neuroscience community and the excellence cluster
@MBExC_de as a tenure-track group leader at the European Neuroscience Institute (ENI-G), where we will continue neural circuit research in a great research environment!
https://mbexc.de/the-mbexc-welcomes-junior-research-group-leader-dr-oliver-barnstedt/
The MBExC welcomes junior research group leader Dr. Oliver Barnstedt – MBExC

MBExC - Multiscale Bioimaging

Oliver BarnstedtDec 2, 2024
Have you ever wondered how memories are processed downstream of the #hippocampus and how this is affected by #Alzheimer's? We believe we may find some answers by riding all the way down the fornix to the mammillary body. Apply here for a #PhD with us: https://ovgu.b-ite.careers/56yvk
425/2024 2 Research Associates (PhD Student) (m/f/d) in Neuroscience

Show threadOliver BarnstedtApr 16, 2024
@eliezyer @naturecomms @petra_moce Hi Eliezyer, thanks for your interest! We have not yet systematically looked at this, but this is definitely one area that deserves closer looking into, given all we know about differential roles of shell/core/lateral/medial/D1/D2. For our retrograde transfection (imaging, ArchT), we have tried to cover much of NAc, including medial shell and core, to avoid too many false negatives. For anterograde transfection (CaMKII-ChR2), we could observe axons in both medial shell and core, not so much lateral shell, but this probably also strongly depends on where exactly in hippocampus you inject (we targeted dorsal prosubiculum). If you're interested, we could write/zoom further to share observations; we're definitely interested in pursuing this further. Much of it was also inspired by Luke's great HPC>NAc cocaine preference paper!
Oliver BarnstedtApr 14, 2024

Excited to say that our paper on #hippocampus-accumbens projection #neurons and their role in spatial reward navigation and appetitive behaviours is now published in @naturecomms :
https://www.nature.com/articles/s41467-024-47361-x
Please see preprint thread for our main findings: https://neuromatch.social/@obarnstedt/110026426575610133

In addition to what we’ve shown in our preprint, we now also show that optogenetic silencing of the dorsal hippocampus-accumbens pathway leads to reduced appetitive licking near the reward zone. Plus, a lot more analysis and statistics in the supplement!

We are now also sharing all our calcium trace and behavioural data with the community: https://zenodo.org/doi/10.5281/zenodo.10698564, along with Jupyter notebooks reproducing all our main figures based on this data: https://github.com/obarnstedt/dHPC-NAc – please write me if you have any questions or queries!

This was a massive team effort with huge help from my supervisor
Stefan Remy, my fantastic colleague @petra_moce, and feedback and encouragement from many friends and colleagues (esp. [email protected]) that have helped carry this through a pandemic, paternity leave, and a lab move.

A hippocampus-accumbens code guides goal-directed appetitive behavior - Nature Communications

The dorsal hippocampus plays an important role for spatial memory, but how its outputs guide behavior is not fully understood. Here, the authors show that nucleus accumbens-specific hippocampal projection neurons carry a highly conjunctive code of spatial and action information that directs spatial reward memory-guided appetitive behaviors.

Nature
Oliver BarnstedtAug 13, 2023
kevinboldingAug 13, 2023
https://www.cell.com/current-biology/pdf/S0960-9822(23)00873-4.pdf Recruitment of grid-like responses in human entorhinal and piriform cortices by odor landmark-based navigation #neuroscience
Oliver BarnstedtJul 28, 2023
Raphael_BritoJul 28, 2023

I guess it's time to finelly do my #introduction !
I'm a PhD student in Michaël Zugaro's lab
I'm studying the interaction between spatial coding in the #hippocampus and reward representation by #dopamine signaling, especially the VTA - Nucleus Accumbens pathway.
Doing ephys extra-cellular recordings in freely mooving rats trying to catch some chocolate milk!
The dying bird convinced me that mastodon was the way to go and I'm glad to see the neuroscience community growing!

I'm a bit shy on social media but I'll boost everything related to the brain that I find interesting 🧠​
#PlaceCell #neuroscience #reward

Oliver BarnstedtMar 29, 2023
Last chance to apply for our 2-week #neuroscience EMBO practical course on in vivo imaging and data analysis!
https://masto.ai/@lindoscope/110105326880487289
LINdoscope (@[email protected])

Attached: 1 image 🔥 DEADLINE EXTENDED! 🔥 Apply until 17 April for our 2-week EMBO #neuroscience practical course on in vivo #imaging (including miniscopes and 2P), #optogenetics, #behaviour, and data #analysis in Magdeburg, Germany: https://meetings.embo.org/event/23-lindoscope#Register We have fantastic speakers lined up including Karel Svoboda, @[email protected], Daniel Dombeck, or @[email protected]. Travel grants and on-site childcare are available! https://masto.ai/@lindoscope/110038172926419911

Mastodon
Oliver BarnstedtMar 29, 2023
LINdoscopeMar 29, 2023
🔥 DEADLINE EXTENDED! 🔥
Apply until 17 April for our 2-week EMBO #neuroscience practical course on in vivo #imaging (including miniscopes and 2P), #optogenetics, #behaviour, and data #analysis in Magdeburg, Germany: https://meetings.embo.org/event/23-lindoscope#Register
We have fantastic speakers lined up including Karel Svoboda, @TrackingActions, Daniel Dombeck, or @antihebbiann. Travel grants and on-site childcare are available!
https://masto.ai/@lindoscope/110038172926419911
LINdoscope: Neuroimaging and data analysis

Advanced optical techniques ushered in a new era of modern neuroscience, enabling basic scientists to interrogate neural activity in behaving animals in unprecedented molecular and anatomical detail.…

Oliver BarnstedtMar 17, 2023
Show threadLINdoscopeMar 17, 2023

Our focus will be on teaching you how to do surgeries and successfully running your own single-photon head-mounted miniscope, two-photon head-fixed imaging, and freely moving optogenetics experiments, and being able to synchronise and analyse this data with behavioural tracking.

We are truly excited for a great line-up of speakers and instructors this year, including Karel Svoboda, @TrackingActions, Daniel Dombeck, @antihebbiann, Valentina Emiliani, Sabine Krabbe, Yunyun Han and more!

Oliver BarnstedtMar 17, 2023
Show threadLINdoscopeMar 17, 2023

There will also be time for some fun and hanging out (see pics from 2021). Previous students had this to say: "honestly, LINdoscope blew my mind. I learned way more than I had even hoped, and formed amazing relationships [...] I would HIGHLY recommend this course to others"

LINdoscope 2023 organisers are Alessio Attardo, Oliver Barnstedt (@obarnstedt), Sanja Mikulovic, and Matthis Prigge from LIN Magdeburg, as well as Janelle Pakan (@PakanLab, OvGU Magdeburg) and Anne Petzold (@neuroadept, UKK)