Nilay Patel 
@theverge.spaceA vote for Donald Trump is a vote for school shootings and measles
An endorsement of democracy, solving problems, and Kamala Harris.
Monell Chemical Senses Center
Philadelphia, PA
| Lab | https://boldinglab.org |
kevinbolding
- 531 Followers
- 663 Following
- 811 Posts
Dylan FestaTootprint! 📄 🤓 I am happy to share my latest preprint (along with some code!), a collaboration with Claudia Cusseddu and Julijana Gjorgjieva in the Gjorgieva lab. https://www.biorxiv.org/content/10.1101/2024.10.12.618014
Inhibitory neurons keep neural circuits stable, preserving the inhibition-stabilized dynamical regime we all like. But they can do more than just provide a blanket of inhibition – they can also form specific excitatory-inhibitory (E/I) connection patterns.
In this work we consider simple inhibitory spike-timing dependent plasticity (STDP) rules (the kind you can implement with a few lines of code in Brian2), and find out that one can achieve both network stabilization and the formation of E/I structures!
Depending on the STDP rule, we get either mutual connections (connecting to excitatory neurons that also connect to them) or lateral connections (targeting excitatory neurons without reciprocal connections). This selectivity depends on how we tune the rule and on the STDP shape. 1/3
Izumi FukunagaNew preprint👃🐭: does timing matter for olfactory coding in the brain, downstream of the olfactory bulb?
We tested the role of sniff rhythms using simple closed-loop optogenetics. Mice can detect spike counts and synchrony, but not so much sniff cycle timing.
Check out Fu et al https://biorxiv.org/cgi/content/short/2024.10.26.620381v1
John Mark OckerbloomThe AP reports that Los Angeles Times editorial page editor resigned after the paper's billionaire owner spiked an endorsement of Harris over Trump: https://apnews.com/article/los-angeles-times-editors-resign-af6c077d502c9d4878bee01fa6575450
CNBC reports that the Washington Post's billionaire owner spiked an endorsement of Harris: https://www.cnbc.com/2024/10/25/jeff-bezos-killed-washington-post-endorsement-of-kamala-harris-.html
The Philadelphia Inquirer isn't owned by a billionaire. Here's its endorsement: https://www.inquirer.com/opinion/editorials/a/endorsement-president-kamala-harris-democracy-20241025.html
Two more LA Times editorial board members resign after the paper withholds a Harris endorsement
Two more members of the Los Angeles Times editorial board have resigned after the newspaper’s owner blocked its plan to endorse Democratic Vice President Kamala Harris for president. Veteran journalists Robert Greene and Karin Klein announced their resignations Thursday, a day after the editorial page editor Mariel Garza left in protest over LA Times owner Dr. Patrick Soon-Shiong’s decision not to endorse a candidate. In an interview with Spectrum News on Thursday, Soon-Shiong pushed back against criticism he censored the editorial board. He said that he feared endorsing a candidate would add to the country’s division.
Jesse Miles@kevinbolding You might be interested in this approach to waveform-based cell type analysis https://doi.org/10.1016/j.xpro.2023.102320
Kenji, who devised the approach, has also been developing an extension that utilizes other physiological features in addition to waveform shape (ISI distribution, PSTH, etc.)
https://www.biorxiv.org/content/10.1101/2024.02.28.582461v1.full
Posted on the neuropixels slack but might as well ask online too. Is anyone going from neuropixels to kilosort to waveform shape analysis for cell type classification? I’m having trouble finding examples.
Carsen Stringer (she/her)📢 #Rastermap paper out now, easily explore and visualize your neural recordings 🐭🐒🐟 and ANNs 🤖 https://nature.com/articles/s41593-024-01783-4. Updates from preprint include analyses of primate data and IBL task data.
Video tutorial: https://youtu.be/oQHq7yUWn2k #Neuroscience #MachineLearning
Outpost Publishers CooperativeJust look at this website!
“Five former Pitchfork journalists are getting the band back together to start a new online music publication, Hearing Things. The site, which launches on Tuesday, aims to capture the original independent spirit of Pitchfork while tuning out the stan armies that worship huge artists.” https://hearingthings.co/
Love the design by Shena Yoshida!
Dirk GütlinPersistent activity during working memory maintenance predicts long-term memory formation in the human hippocampus
#Neuroscience #CogSci
www.cell.com/neuron/fullt...
Persistent activity during wor...
Persistent activity during wor...
Nicole RustI'm looking for papers that map individual differences in behavior onto neural data. Like this one by Valeria Fascianelli, Stefano Fusi ++. Any type of creature; any type of mapping. Know any?
Neural representational geometries reflect behavioral differences in monkeys and recurrent neural networks - Nature Communications
Traditionally, studies focused on neural features conserved across subjects, with little attention to differences. Here, the authors show it is possible to identify differences in neural geometry linked to behavioral differences in monkeys and RNNs.