Max Heckelmann from the group of Don Hilvert presented his research at #Biochemistry2026. He talked about the "Generation and Evolution of de novo Designed Chorismate Mutases".

#ProteinDesign #Evolution #Biochemistry #ChemBio #Chemistry
CC: @gdch

Can proteins with a certain function be designed from scratch?

Interesting talk by Birte Höcker at #Biochemistry2026. She talked about her group's research on "Design for function - building enzymes from scratch".

https://www.nature.com/articles/s41467-022-32007-7
#ProteinDesign #Biochemistry #Chemistry #ChemBio #AI
CC: @gdch

Get to know Thomas Schlichthärle, our newly appointed professor of #AI-guided #ProteinDesign, in the latest NewIn episode. He wants to use custom-designed #proteins to advance the development of new #medicines: http://go.tum.de/484027

#HightechAgendaBayern

▶️ https://youtu.be/G-pt28HJpA8

📹& 📷ProLehre

Designing proteins for targeted cell activation

Custom-designed proteins that can control cells and activate them in a targeted way: Thomas Schlichthärle wants to use them to advance the development…

BoltzGen là mô hình AI đột phá, thiết kế protein và peptide (binder) để gắn kết đa dạng mục tiêu sinh học. Nó tích hợp thiết kế và dự đoán cấu trúc, đạt hiệu suất cao và được xác thực thực nghiệm, mở ra tiềm năng lớn cho y học và sinh học.

#BoltzGen #AI #ProteinDesign #DrugDiscovery #ThiếtKếThuốc #CôngNghệSinhHọc

https://www.reddit.com/r/singularity/comments/1p7npos/boltzgen_toward_universal_binder_design/

Neural network finds an enzyme that can break down polyurethane

Given a dozen hours, the enzyme can turn a foam pad into reusable chemicals.

Ars Technica

Our university established professorships in #Marketing & Technology and #AI-guided #ProteinDesign, supported by the Wübben Stiftung Wissenschaft. The professorships were appointed to David Finken and Thomas Schlichthärle (pictured): http://go.tum.de/670372

📷A.Eckert

New endowed professorships for marketing and protein design

With the support of the Wübben Stiftung, TUM has established a professorship for Marketing & Technology and a professorship for AI-guided Protein Design.

💡 AI can predict protein structures — but can it predict how they behave?

🔗 AlphaFold3 prediction of protein-protein complex: Is it ready for thermodynamic analysis?. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.015

📚 CSBJ: https://www.csbj.org/

#AlphaFold3 #ProteinDesign #MolecularModeling #ComputationalBiology #StructuralBiology #Thermodynamics #ProteinProteinInteractions #Bioinformatics

Do AI-designed proteins create a biosecurity vulnerability? https://arstechni.ca/8znR #riskassessment #proteindesign #bioterrorism #biohazards #security #Science #AI
A biological 0-day? Threat-screening tools may miss AI-designed proteins.

Ordering DNA for AI-designed toxins doesn’t always raise red flags.

Ars Technica