Mastodawn

Breakthrough in tailor-made enzyme design
https://www.uni-bayreuth.de/en/press-releases/tailor-made-enzyme
#Research #Enzymes #ProteinDesign #Biotechnology #Sustainability #UniversityOfBayreuth

Breakthrough in tailor-made enzyme design

Enzymes are regarded as the key to sustainable chemistry. Despite major advances in protein design, creating artificial enzymes from scratch has so far remained a grand challenge. A research team at the University of Bayreuth, in collaboration with scientists from the University of Ottawa, has now demonstrated how non-functional protein scaffolds can be transformed into highly active enzymes. The researchers report their findings in the prestigious journal Nature Chemical Biology.

CSBJ Jun 9

🤖 Have we built AI powerful enough to design proteins, but too complicated for most scientists to use?

🔗 BioPipelines: Accessible Computational Protein and Ligand Design for Chemical Biologists. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0129

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#BioPipelines #ProteinEngineering #ComputationalBiology #ProteinDesign #SyntheticBiology #Bioinformatics #AlphaFold #SystemsBiology #AI

CSBJ Jun 9

🦠 Can a redesigned bacterial platform reshape the future of protein engineering?

🔗 Optimized Quantitative Bacterial Two-Hybrid (qB2H) for Protein–Protein Interaction Assessment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0098

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#ProteinEngineering #SyntheticBiology #ProteinDesign #DrugDiscovery #ProteinInteractions #TherapeuticDiscovery

de.NBI & ELIXIR Germany May 22

🧬 Registration is OPEN! Leipzig #Rosetta Workshop 2026! Learn theoretical baselines & gain hands-on experience with cutting-edge technologies.
📅 17–21 Aug 2026
📍 Scads.AI, Leipzig
💰 FREE (All career levels welcome)
💻 Prereqs: Basic Python/Bash
🔬 Tools covered: AlphaFold and many more
🔥 Special for 2026: Enriched program focusing on new RosettaCommons tech + an interactive hackathon session!
🔗 Secure your spot now: [https://www.denbi.de/training-courses-2026/2072-leipzig-rosetta-workshop
#ProteinDesign #DrugDiscovery #AlphaFold #Bioinformatics

WiSoFakultät_UniKöln May 12

🚀 PhD opportunity at the Cologne Institute for Information Systems (CIIS)!

Doctoral Researcher / Research Assistant in AI-driven Protein Design (f/m/x)

🧬 AI + Protein Design + ML
📍 University of Cologne
⏳ Apply by 25 May 2026

🔗 https://uni.koeln/Z83TB

#AI #PhD #ProteinDesign #MachineLearning

amplisci Apr 6

##New PhD opportunity##

Position: PhD in De novo design of ice-binding proteins

Location: Eindhoven, Netherlands

Deadline: 30 Apr 2026

Description: The role focuses on engineering ice-binding proteins (IBPs) to control ice nucleation and growth, with applications in biomedical cryopreservation (e.g., heart and kidney). The project combines computational protein design (Rosetta, AlphaFold, ML) with biochemical and structural biology techniques.

Key Requirements: 1. Master’s in Molecular Life Sciences, Biophysics, or related field.
2. Background in de novo protein design, structure prediction, and coding (Python/C++).
3. Interest in biophysics/soft matter science.

Offer: • 4-year full-time contract (scale P) • International environment in the Brainport tech region • Teaching component (~10%)

Contact: Prof. Dr. Ir. Ilja Voets ([email protected])

Application link: https://tue.varbi.com/en/apply/positionquick/922122/?where=55

#PhD #phdposition #ProteinDesign #Cryobiology #AcademicJobs

You are applying for: PhD in De novo design of ice-binding proteins

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GDCh Division of Biochemistry Mar 17

Max Heckelmann from the group of Don Hilvert presented his research at #Biochemistry2026. He talked about the "Generation and Evolution of de novo Designed Chorismate Mutases".

#ProteinDesign #Evolution #Biochemistry #ChemBio #Chemistry
CC: @gdch

GDCh Division of Biochemistry Mar 17

Can proteins with a certain function be designed from scratch?

Interesting talk by Birte Höcker at #Biochemistry2026. She talked about her group's research on "Design for function - building enzymes from scratch".

https://www.nature.com/articles/s41467-022-32007-7
#ProteinDesign #Biochemistry #Chemistry #ChemBio #AI
CC: @gdch

Technische Universität München Feb 24

Get to know Thomas Schlichthärle, our newly appointed professor of #AI-guided #ProteinDesign, in the latest NewIn episode. He wants to use custom-designed #proteins to advance the development of new #medicines: http://go.tum.de/484027

#HightechAgendaBayern

▶️ https://youtu.be/G-pt28HJpA8

📹& 📷ProLehre

Designing proteins for targeted cell activation

Custom-designed proteins that can control cells and activate them in a targeted way: Thomas Schlichthärle wants to use them to advance the development…

Show thread

James Jan 3

Original essay + hashtags:
https://www.science.org/doi/10.1126/science.ado1671

#AI #Biosecurity #ProteinDesign #ArtificialIntelligence #Science #SyntheticBiology