We bumped into #preLighter and former intern (also @the_node & @focalplane_jcs) Ryan Harrison. πŸ™Œ #biologists100

Here, he presented a beautiful (pink 🀩) poster detailing his work on cell organisation & 3D shape emergence in a posterior neuruloid system. ✨

#organoids #development #ECRs #preprints

On how membrane curvature allows our hearts to beat… πŸ’“

#preLighter Barbora Knotkova highlights beautiful work from Yang Yang & colleagues #preprint

#preLight + author response ⬇️ πŸ‘€

https://prelights.biologists.com/highlights/membrane-curvature-promotes-er-pm-contact-formation-via-junctophilin-ehd-interactions/

#biology #heart #cells #curvature #membranes

The PLK1 kinase mandates DNA polymerase theta to safeguard the #genome during #mitosis.

#preLighter Pierre Caron covers a #preprint by Camille Gelot #institut_curie and team that redefines the physiological function of #TMEJ.

#DNArepair #GenomeStability
https://prelights.biologists.com/highlights/pol%ce%b8-is-phosphorylated-by-polo-like-kinase-1-plk1-to-enable-repair-of-dna-double-strand-breaks-in-mitosis/

PolΞΈ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis - preLights

The PLK1 kinase mandates DNA polymerase theta to safeguard the genome during mitosis.

preLights

Missed the 9th International Symposium on the Biology of Vertebrate Sex Determination last week? #VSDHawaii2023

#preLighter Martin Estermann has put together a #preList containing #preprints that were discussed and presented there.

πŸ“œ preList: https://prelights.biologists.com/prelists/9th-international-symposium-on-the-biology-of-vertebrate-sex-determination/

Helping funders & institutions as they consider #OpenScience implementation.

Kristen Ratan and colleagues discuss their approach at #ASAP_Research to incorporate open science policies and advance science through reuse and collaboration. #preprint

Great new #preLight from Kanika Khanna!

πŸ‘‰ https://prelights.biologists.com/highlights/from-policy-to-practice-tracking-an-open-science-funding-initiative/

#preLighter #ASAPbio_Fellow

Roses are red, violets are blue, when the disk proper grows, hippo stretches peripodial epithelium too. 🌹

A new post from Girish Kale covering a #preprint led by another #preLighter: Sophia Friesen who works in the #HariharanLab

Check it out! πŸ‘‰ https://prelights.biologists.com/highlights/coordinated-growth-of-linked-epithelia-is-mediated-by-the-hippo-pathway/

Two new posts on preLights today! πŸ‘€

The first has been written by our new #preLighter Yueh Cho (postdoc at #IPMBSinica & #AcadSinica) who covers a #preprint from Tina Schreier and colleagues which shows that light and photosynthesis trigger plasmodesmal formation in C4 dicotyledons 🌱

πŸ“œ https://prelights.biologists.com/highlights/plasmodesmal-connectivity-in-c4-gynandropsis-gynandra-is-induced-by-light-and-dependent-on-photosynthesis/

#plants #grasses #dicotyledons #plasmodesmata

An inducible tagging strategy to label proteins enables nanometer-scale localisation of molecules in human cells. #cryo-ET #FluorescenceMicroscopy. πŸ”¬

πŸ“œ https://prelights.biologists.com/highlights/genetically-encoded-multimeric-tags-for-intracellular-protein-localisation-in-cryo-em/

#preLighter Martyna Kosno-Vega covers an exciting #preprint from the #MahamidLab #EMBLHeidelberg.

#biochemistry #bioengineering #imaging #biophysics

Happy New Year! πŸŽ† Two preLights to kick off 2023.

2nd: urban-adapted mosquitoes may spread malaria to new regions as the Earth warms 🦟🌎 - an important (and alarming) #preprint from Sadie J. Ryan, Catherine A. Lippi and colleagues.

By #preLighter Sophia Friesen #HariharanLab #Berkeley

πŸ“œ https://prelights.biologists.com/highlights/mapping-current-and-future-thermal-limits-to-suitability-for-malaria-transmission-by-the-invasive-mosquito-anopheles-stephensi/

Happy New Year! πŸŽ† Two new #preLights to kick off #2023.

1st: It’s all clicking together - Keqing Nian, Yifang Liu, Laura Brigandi & Sara H. Rouhanifard develop a DNA oligomer-conjugated ligand for copper-catalysed azide-alkyne cycloadditions.

By #preLighter @zhanghe_goh #EPSRC #CDT #Cambridge

πŸ“œ https://prelights.biologists.com/highlights/dna-enhanced-cuaac-ligand-enables-live-cell-detection-of-intracellular-biomolecules/