Yesterday session on #Clostridia #phages and surfaces was brilliant, with personal highlights being Dr Anna Barwinska-Sendra's work on diversification of #Cdiff #S-layers, Louis-Charles Fortier's talk on how phage/S-layer specificity and Lea Huet's work in PSII S-layer anchoring. #clostpath14

Gut #microbiota and #neurological effects of #glyphosate

by Lola Rueda-Ruzafa , Francisco Cruz, Pablo Roman, Diana Cardona

August, 2019

"There are currently various concerns regarding certain #environmental #toxins and the possible impact they can have on developmental diseases. #Glyphosate (Gly) is the most utilised #herbicide in #agriculture, although its widespread use is generating controversy in the scientific world because of its probable carcinogenic effect on human cells. Gly performs as an inhibitor of 5-enolpyruvylshikimate-3-phospate synthase (EPSP synthase), not only in plants, but also in bacteria. An inhibiting effect on EPSP synthase from intestinal microbiota has been reported, affecting mainly beneficial bacteria. To the contrary, Clostridium spp. and Salmonella strains are shown to be resistant to Gly. Consequently, researchers have suggested that Gly can cause #dysbiosis, a phenomenon which is characterised by an imbalance between beneficial and pathogenic #microorganisms. The overgrowth of bacteria such as #clostridia generates high levels of noxious metabolites in the #brain, which can contribute to the development of neurological deviations. This work reviews the impact of Gly-induced intestinal #dysbiosis on the central nervous system, focusing on emotional, neurological and #neurodegenerative disorders. A wide variety of factors were investigated in relation to brain-related changes, including highlighting #genetic abnormalities, pregnancy-associated problems, diet, infections, vaccines and heavy metals. However, more studies are required to determine the implication of the most internationally used herbicide, Gly, in behavioural disorders."

https://pubmed.ncbi.nlm.nih.gov/31442459/

#Monsanto #EU #USA #Canada #Roundup

Gut microbiota and neurological effects of glyphosate - PubMed

There are currently various concerns regarding certain environmental toxins and the possible impact they can have on developmental diseases. Glyphosate (Gly) is the most utilised herbicide in agriculture, although its widespread use is generating controversy in the scientific world because of its pr …

PubMed
Your microbes live on after you die − a microbiologist explains how your necrobiome recycles your body to nourish new life

Raw Story - Celebrating 19 Years of Independent Journalism

2019: #Gut #microbiota and #neurological effects of #glyphosate

Abstract: "There are currently various concerns regarding certain environmental toxins and the possible impact they can have on developmental diseases. Glyphosate (Gly) is the most utilised herbicide in agriculture, although its widespread use is generating controversy in the scientific world because of its probable #carcinogenic effect on human cells. Gly performs as an inhibitor of 5-enolpyruvylshikimate-3-phospate synthase (EPSP synthase), not only in plants, but also in bacteria. An inhibiting effect on EPSP synthase from intestinal microbiota has been reported, affecting mainly beneficial bacteria. To the contrary, Clostridium spp. and Salmonella strains are shown to be resistant to Gly. Consequently, researchers have suggested that Gly can cause dysbiosis, a phenomenon which is characterised by an imbalance between beneficial and pathogenic microorganisms. The overgrowth of bacteria such as #clostridia generates high levels of noxious metabolites in the #brain, which can contribute to the development of neurological deviations. This work reviews the impact of Glyphosate-induced #intestinal dysbiosis on the central nervous system, focusing on emotional, #neurological and #neurodegenerative disorders. A wide variety of factors were investigated in relation to brain-related changes, including highlighting #genetic abnormalities, #pregnancy-associated problems, #diet, #infections, vaccines and heavy metals. However, more studies are required to determine the implication of the most internationally used #herbicide, Gly, in behavioural disorders."

#RoundUp #Herbicides #Soy #Wheat #Corn

Read more:
https://pubmed.ncbi.nlm.nih.gov/31442459/

Gut microbiota and neurological effects of glyphosate - PubMed

There are currently various concerns regarding certain environmental toxins and the possible impact they can have on developmental diseases. Glyphosate (Gly) is the most utilised herbicide in agriculture, although its widespread use is generating controversy in the scientific world because of its pr …

PubMed

For the next step in dealing with allergenic reactions is to successfully have the body's gut microbiome produce an abundance of anti-allergenic molecules.

Researchers at the University of Chicago have used polymeric micelles containing anti-allergen butyrate to cause gut Clostridia that also makes it to proliferate, preventing anaphylactic shock in mice from peanuts.

#Allergies #Allergens #Butyrate #Clostridia #Mice #Microbiome #Microbiology #Science #Scicomm

https://www.nature.com/articles/s41551-022-00972-5

Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles - Nature Biomedical Engineering

Intragastrically delivered polymeric micelles releasing butyrate along the intestinal tract restore barrier-protective responses in mouse models of peanut allergy and colitis.

Nature