We are very happy that Thomas Clairfeuille from Roche visited us today for a very well attended LED3 Lecture. He talked about "The discovery and mechanism of lipid transport inhibition by the antibiotic Zosurabalpin".

https://www.nature.com/articles/s41586-023-06873-0
#Antibiotics #DrugDiscovery #ChemBio #Chemistry

Interesting ChemRxiv preprint by the group of Tom Wennekes with first author Jun Yang Ong. They show that chlorotriazine (ClTriZ) reactive groups are compatible with dual click direct-to-biology (D2B) approaches and can yield potent and selective protein labeling tools.

https://chemrxiv.org/doi/full/10.26434/chemrxiv-2025-4kzhd
#Chemistry #ChemBio #Glycotime #D2B

Amazing talk by Jana Volaric from our Molecular Physiology Department and @LED3hub at #KNCVMCCB2026. She talked about her postdoctoral research in the Ed Tate lab into optical control of S-acyltransferase activity in mammalian cells.

#Chemistry #ChemBio #GeneticCodeExpansion

Laura Wijffelaars gave an interesting talk at #KNCVMCCB2026. She talked about her research into an ACKR3 inverse agonist with potential in the treatment of #MultipleSclerosis.

#Chemistry #ChemBio #DrugDiscovery #MS

Interesting talk by Karlijn Meerman at #KNCVMCCB2026. She talked about her #PhD research in the group of Ben Feringa about making photoswitchable cyclic peptides in collaboration with Nathaniel Martin of our @LED3hub.

#Chemistry #ChemBio #Peptides #PhotoSwitch