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Leiden Early Drug Discovery & Development (LED3) is a hub of scientists working on early drug discovery at the Leiden Institute of Chemistry, the Leiden Academic Centre for Drug Research, the Institute of Biology Leiden and the Leiden Institute of Advanced Computer Science.
Homepagehttps://www.universiteitleiden.nl/en/science/led3
Homepagehttps://www.universiteitleiden.nl/en/science/led3/led3-lectures
Blueskyhttps://bsky.app/profile/led3hub.bsky.social
Twitterhttps://twitter.com/LED3hub

Inspiring @LED3hub Lecture by Madelon Maurice. She talked about SureTACs as a modality for lysosomal degradation of membrane proteins by engaging membrane-bound E3 ligases using antibodies.

https://worldwide.espacenet.com/patent/search/family/074844924/publication/US2023142972A1?q=pn%3DUS2023142972A1

#Chemistry #ChemBio #DrugDiscovery #TPD #Degrader

We are very happy that Madelon Maurice from UMC Utrecht and Oncode Institute visited us today for a LED3 Lecture. She talked about "SureTACs: A novel modality for targeted degradation of cell surface proteins".

#DrugDiscovery #TPD #Degraders #ChemBio #Chemistry

RE: https://mstdn.science/@LED3hub/116769930240116706

Check out the program for the @LED3hub Lectures of the coming academic year. It would be great to see many of you there!

We want to thank the organizers of this lecture series for putting this amazing program together:
Anne Wentink
Sandra Irmisch
Nathaniel Martin
Sebastian Pomplun
Kim Bonger
Rob van Wijk
Stephan M. Hacker
(7/7)
June 24th, 2027
LED3 PhD/Postdoc Symposium #LED3Symposium
Keynote Lecture: Eda Canales, Gilead Sciences
A twice-yearly injection offering near-total protection against HIV infection
(6/7)

April 22nd, 2027 – 16:00
Dek Woolfson, University of Bristol
Designer proteins

May 27th, 2027 – 16:00
Gunda Georg, University of Minnesota
A hormone-free male birth control pill
(5/7)

March 4th, 2027 – 16:00
Don Mager, University at Buffalo
Translational PKPD for novel modalities

March 18th, 2027 – 16:00
Bryan Roth, The University of North Carolina at Chapel Hill
GPCR structure, function and pharmacology
(4/7)

November 26th, 2026 – 16:00
Jan Steyaert, Vrije Universiteit Brussel
Nanobody discovery and engineering

January 28th, 2027 – 16:00
Christina Baumgartner, AbbVie
Phosphatase inhibitors for oncology
(3/7)

September 24th, 2026 – 16:00
Christian P.R. Hackenberger, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)
P5-labeling for Generating Highly Efficacious ADCs

October 29th, 2026 – 16:00
Marc Robillard, Tagworks Pharmaceuticals
Click-cleavable antibody-drug conjugates
(2/7)

We are excited that we could again invite a world-class program of speakers for the LED3 Lectures 2026/2027.

Full program below. All current information can be found here: https://www.universiteitleiden.nl/en/science/led3/led3-lectures

Let us know in the comments, which lectures you are mot looking forward to! (1/7)