I had the great opportunity to present some of our group's recent work at @[email protected]. Thank you to @[email protected] and Stephen Burley for inviting me and to all that took the time to attend. #ChemicalProteomics #ChemPro #Presenting #Science #ChemSky

A couple of weeks back I had the great opportunity to present some of our group's recent work in a virtual presentation at Rutgers University. A huge thank you to Joel Freundlich and Stephen Burley for inviting me (and for the gift that I just received). Thank you also to all that took the time to attend and participate in the discussion.

#ChemicalProteomics #ChemPro #Presenting #Science #Chemistry

RE: https://mstdn.science/@ABPP2027/116136570431382767

#ABPP2027 will be happening in Leiden on June 2nd to 4th, 2027.

I am very excited to be part of the organization together with an amazing team.

Sign up for our mailing list here: https://www.universiteitleiden.nl/en/science/led3/abpp2027

#ABPP #ChemoProteomics #ChemPro #ProteoProbes #Chemistry #ChemBio #DrugDiscovery

#ABPP2027 will be happening in Leiden on June 2nd to 4th, 2027. I am excited to be part of the organization together with an amazing team. Sign up for our mailing list here: www.universiteitleiden.nl/en/science/l... #ABPP #ChemoProteomics #ChemPro #ProteoProbes #ChemSky #ChemBio #DrugDiscovery

RE: https://bsky.app/profile/did:plc:4tytwyqkv6ha2gxkkc6bitq5/post/3mfqzuvrrb22h

We are super excited that the 15th Activity-based protein profiling conference #ABPP2027 will take place in the Naturalis in Leiden on June 2nd to 4th, 2027.

Mark your agendas for this exciting event!

To not miss anything, sign up for our mailing list here: https://www.universiteitleiden.nl/en/science/led3/abpp2027

#ABPP #ChemoProteomics #ChemPro #ProteoProbes #Chemistry #ChemBio #DrugDiscovery

Interesting paper by the group of Rolf Breinbauer in Organic & Biomolecular Chemistry. They synthesized three α-fluoromethyl naphthoquinone-based probes as potentially reduction-activated probes for oxidoreductases, but found promiscuous reactivity.

https://pubs.rsc.org/en/content/articlelanding/2025/ob/d5ob01320h
#Chemistry #ChemBio #ABPP #ChemPro #ProteoProbes #ChemicalProteomics

Very excited to see this study by the group of David Konrad out in JACS Au.

Ortho-dichloroacrylophenone is a highly reactive, cysteine-directed electrophile for peptide and protein labeling as well as chemoproteomic profiling. Glad that our group could make a small contribution.

https://pubs.acs.org/doi/10.1021/jacsau.5c00692
#ChemBio #Chemistry #ChemPro #ProteoProbes #CovalentInhibitors

Interesting bioRxiv preprint by the groups of Liron Bar-Peled and A. John Iafrate. They introduce COUPLrs - structurally diverse molecules with 2 electrophilic warheads and an alkyne - to identify proteins that can be linked to other proteins. https://www.biorxiv.org/content/10.1101/2024.07.16.603666v1
#Chemistry #ChemBio #ChemPro #InducedProximity