No More Endless Boosters? Scientists Develop One-for-All Virus Vaccine
End of the line for endless boosters? Researchers at UC Riverside have developed a new vaccine approach using RNA that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised. Every year, researchers try to predict the four influenza strains that
Antibiotic Zevtera (Ceftobiprole medocaril) approved by FDA for treatment of CABP, ABSSSI and SAB
The broad-spectrum fifth-generation cephalosporin antibiotic, Zevtera (Ceftobiprole medocaril sodium Inj.) has been approved by FDA1 for the treatment of thre
#Harmonine is a defense compound produced by the #Asian #ladybeetle #Harmoniaaxyridis
It is an important factor in beetle #immunity and has #BroadSpectrum #antimicrobial #activity #inhibiting the growth of #mycobacteria and demonstrating #multistage #antimalarial activity
The Asian lady beetle uses harmonine as a general hygiene measure, but switches to an effective defense strategy based on dozens of peptides when threatened
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297383/
https://www.mpg.de/7246516/Asian-lady-beetles
Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity
The harlequin ladybird beetle Harmonia axyridis has been introduced in many countries as a biological control agent, but has become an invasive species threatening the biodiversity of native ladybirds. Its invasive success has been attributed to its vigorous ...
#Nucleoside #chemistry is where I started more than 20 years ago as a young MedChem student in the group of Maurizio Botta.
A back to the future adventure has brought us today to this new paper on
#ChemMedChem.
We have tried to teach these old dogs new tricks for the development of
#broadspectrum #antimicrobial agents.
#MedChem #DrugDiscovery #Antiviralhttps://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202300200 
Iboxamycin (IBX): a Synthetic Broad-Spectrum Antibiotic to address Anti-Microbial Resistance (AMR)
Development of multi-drug resistance (MDR) bacteria in the past five decades have led to increasing research in search of a drug candidate to address
Matt Willemsen
Scientific European
🐦🔥nemo™🐦⬛ 🇺🇦🍉
Marco Radi