Bats harbor many #zoonotic #viruses yet remain asymptomatic; why? @Lucie_Virevolte &co show that #bat GBP5 evolved under +ve selection, driving virus-specific restriction & lineage-specific loss of a #prenylation motif that reshaped #antiviral function @PLOSBiology https://plos.io/48KVgYe

Non-spike changes driving #SARS-CoV-2 fitness remain unknown. This Primer explores two @PLOSBiology papers showing that N gene mutations create a truncated N protein that enhances fitness by blocking #antiviral responses. Papers: https://plos.io/3PIZMjr https://plos.io/4jyUAco Primer: https://plos.io/4cnGhG8

#SARSCoV2 has evolved to optimize its replication fitness in the human host. This study shows that a #nucleocapsid gene mutation enhances production of a truncated protein that boosts viral fitness by suppressing #antiviral responses @PLOSBiology https://plos.io/3PIZMjr

Prompt and Intensive #Antiviral #Chemoprophylaxis in Nursing Home #Influenza #Outbreaks, https://etidiohnew.blogspot.com/2026/03/prompt-and-intensive-antiviral.html

Use of #baloxavir as adjunctive #antiviral #therapy to neuraminidase inhibitors in severely immunocompromised individuals infected with #influenza, https://etidiohnew.blogspot.com/2026/03/use-of-baloxavir-as-adjunctive.html

Aloe Vera is characterized by increased antiviral properties #aloevera #antiviral #aloeverabenefits ... Continue to: https://www.facebook.com/reel/1463668085341431/

14th Meeting of #WHO #Expert Working Group of the Global #Influenza #Surveillance and Response System (GISRS) for Surveillance of #Antiviral Susceptibility (March 20 '26), https://etidiohnew.blogspot.com/2026/03/14th-meeting-of-who-expert-working.html

🧪Phillyrin is a unique #antiviral lignan with potent anti-#flu activity only found in Forsythia suspensa.
Wang et al. reveal key steps in its #biosynthesis, bringing us one step closer to a valuable #drug.
🔗https://doi.org/10.1111/jipb.70216
@WileyLifeSci
#PlantSci #JIPB #plant #medicine #botany

How can we study the function of nucleotide-based #SecondMessengers? @[email protected] presented her group's exciting findings in this field at #Biochemistry2026. She e.g. presented the #cryoEM structure of OAS2, which has key #antiviral functions. linkinghub.elsevier.com/retrieve/pii...