michaelfirst #clinicalTrial for #aptamer sensors enabling continuous #monitoring of therapeutic drugs in vivo - my news story in #ChemistryWorld out now: https://proseandpassion.blogspot.com/2026/02/aptamer-sensors-patched-up.html
🐦🔥nemo™🐦⬛ 🇺🇦🍉Was zur Hölle ist ein #aptamer 🤔
Ein Aptamer ist ein kurzes einzelsträngiges DNA- oder RNA-Oligonukleotid, das spezifisch an ein Zielmolekül binden kann. Diese Moleküle können Proteine, bakterielle Gifte, niedermolekulare Stoffe wie Aminosäuren, Antibiotika und Viruspartikel binden. Aptamere werden künstlich in vitro hergestellt und weisen Dissoziationskonstanten im pico- bis nanomolaren Bereich auf.
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#BC007 ist ein potenzieller Wirkstoffkandidat gegen das #PostCovidSyndrom und andere #Autoimmunkrankheiten mit funktionellen Autoantikörpern gegen #GProtein gekoppelte Rezeptoren #gpcr Es handelt sich um ein #aptamer das diese krankmachenden #Autoantikörper blockieren soll. Die klinische Phase-II-Studie reCOVer der Augenklinik des #Uniklinikums #Erlangen untersucht den molekularen Weg bestimmter Autoantikörper beim Post-COVID-Syndrom. In diesem Zusammenhang startet in …
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CellBioNewsNovel approach uses #ionic #liquids for diverse #aptamer applications.
https://phys.org/news/2024-01-approach-ionic-liquids-diverse-aptamer.html
Novel approach uses ionic liquids for diverse aptamer applications
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as well as their ability to inhibit specific enzymes or target proteins through three-dimensional binding.
#DNA #aptamer finds novel application in #regulating #cell #differentiation .
https://phys.org/news/2023-10-dna-aptamer-application-cell-differentiation.html
DNA aptamer finds novel application in regulating cell differentiation
Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine. Guiding iPSCs toward a target cell line has garnered much attention, but the process remains challenging.
katch wrecknew citation: `Real-time label-free #detection of dynamic #aptamer–small #molecule interactions using a #nanopore nucleic acid conformational #sensor`
Phys.orgReferenced link: https://phys.org/news/2023-05-chemicals-brain-aptamermicroelectronic-fiber-combination.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-05-chemicals-brain-aptamermicroelectronic-fiber-combination.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1658837098621747204#m
Reading chemicals inside the #brain with an #aptamer/microelectronic fiber combination @tohoku_univ https://pubs.acs.org/doi/10.1021/acs.analchem.2c05046 https://phys.org/news/2023-05-chemicals-brain-aptamermicroelectronic-fiber-combination.html
Reading chemicals inside the brain with an aptamer/microelectronic fiber combination
A research group has developed a neural device that detects specific neurotransmitters in the brain with high sensitivity and selectivity by combining multifunctional fibers and DNA molecular probes. Details of the research were published in the journal Analytical Chemistry on April 24, 2023.
Ben MeekinsDid you miss this great talk from
@breadascientist? Check it out on Youtube: https://youtu.be/hIQUIlenzxY
#scicomm #openscience #STEM #aptamer #chemistry #chemtwitter #biochemistry #science #education #VLP
@breadascientist? Check it out on Youtube: https://youtu.be/hIQUIlenzxY
#scicomm #openscience #STEM #aptamer #chemistry #chemtwitter #biochemistry #science #education #VLP
Dr. Brea Manuel (UMBC): "Modular Catalysis: Aptamer Enhancement of Enzyme Kinetics in an NP Reactor"
this must be the first time I've seen the word #aptamer on the front page of the guardian website:
https://www.theguardian.com/business/2022/dec/25/aptamer-york-biotech-cancer-treatments