stjuderesearchMay 19, 2023
Developing new treatments for #ChildhoodCancer requires creative solutions. #StJude #scientists are pushing the boundaries of what is possible by designing compounds that degrade proteins. Read about the #technology and discoveries. https://bit.ly/3NP9GNs #StJudeON #StJudeResearch
Targeted protein degradation to treat cancer

St. Jude scientists are identifying targets and designing drugs to degrade proteins implicated in hard-to-treat cancers. Learn about creating PROTACs.

Stjude Blogs
DiverseTCRMar 22, 2023
Powerful tools to understand complex biology #TCR #specificity and #diversity @PGTimmune
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RT @StJudeResearch
There are many kinds of T cells: CD4+ vs. CD8+, effector vs. memory. But how did researchers figure out what they all do? St. Jude scientists use various methods, including some they created themselves. http://bit.ly/40tLT8Z @beiyun_liu @PGTimmune #StJudeOn
https://twitter.com/StJudeResearch/status/1638255696356470804
How scientists visualize and analyze T cells

Watch St. Jude scientists explain how the tools they use to study T cells work, including CoNGA an analysis created in the laboratory of Paul Thomas, PhD.

Stjude Blogs
stjuderesearchMar 21, 2023
There are wide varieties of #TCells: CD4+ vs. CD8+, effector vs. memory. As there are countless health threats for our T cells to resist, including #viruses and #cancer, how did #scientists figure out how T cells properly function to protect us? Discover how #StJude #immunologists use various methods, including some they created themselves, to track and analyze T cells and their function better. http://bit.ly/40tLT8Z #StJudeON #StJudeResearch
How scientists visualize and analyze T cells

Watch St. Jude scientists explain how the tools they use to study T cells work, including CoNGA an analysis created in the laboratory of Paul Thomas, PhD.

Stjude Blogs
stjuderesearchMar 14, 2023
#CARTcell #therapy is a promising #immunebased #treatment approach. Explore how #scientists at #StJude are working to optimize #CARTCellTherapy to better meet all #cancer patients' needs. http://bit.ly/3Lnw8Md #StJudeOn
Engineering a new kind of therapy

Scientists at St. Jude are leading research on chimeric antigen receptor (CAR) T cells to develop novel immunotherapy strategies for childhood cancer.

Stjude Blogs
stjuderesearchMar 7, 2023
How does a #TCell know that it’s a T cell? How does a T cell know what to do to protect us from #infection and #disease? #Scientists at #StJude are unraveling the complex #biology behind these processes. Read the blog post. http://bit.ly/3SWhlKb #StJudeON #Immunotherapy #StJudeResearch
Understanding the complex networks behind a functional adaptive immune system

Read the St. Jude On T cells series article on Fate and Function to learn how a T cell knows what it is and how it knows what to do to protect us.

Stjude Blogs
stjuderesearchFeb 28, 2023
Scientists at #StJude are studying the many parts of the immune system to better understand how our body protects us from infections and diseases. https://bit.ly/3KS41o6 #StJudeON #StJudeResearch
Immunity in the spotlight: how vaccinations and the immune system protect us

Vaccinations and the immune system protect us from infections and illness. Find out how immunity works and what scientists at St. Jude have learned about it.

Stjude Blogs
stjuderesearchFeb 7, 2023
Studying genomics means creating #bigdata. Scientists at #StJude have developed many tools and techniques to tackle big to tackle data challenges with cutting-edge visualizations and analysis. Learn more. https://bit.ly/3EcZUPJ #StJudeON #StJudeResearch #ComputationalBiology
stjuderesearchJan 24, 2023
DNA isn't destiny, but genetic predispositions do underlie many cancers. #StJude scientists have gained a nuanced understanding of cancer predisposition and are learning more to help personalize patient therapies. http://bit.ly/3H1WIqF #StJudeOn #StJudeResearch
Genetic predispositions can drive cancer but are not destiny for patients

Scientists at St. Jude are leading the way on understanding cancer predisposition and the way that inherited genetics can inform patient care.

Stjude Blogs
stjuderesearchJan 18, 2023

Everything has a weakness, including cancer. St. Jude scientists are hunting for the “holy grail” of cancer vulnerabilities. Read how St. Jude is pioneering discoveries in this area. https://bit.ly/3WdagoI

#StJudeOn #StJude #StJudeResearch #CancerResearch

St. Jude scientists on the hunt for ‘holy grail’ cancer vulnerabilities

Scientists at St. Jude Children’s Research Hospital are deploying genomic technologies to hunt for vulnerabilities in cancer.

Stjude Blogs
stjuderesearchJan 10, 2023

Come take a deep dive with us as our new series explores a variety of topics within biomedical research including genetics, T cells, transcription and more. The first in our #StJudeON series: the relationship between #cancer and #genetics.

From the Pediatric Cancer Genome Project and beyond, #StJude has a long history of genetic discovery. Read about the work of our scientists on the genetics of vulnerabilities, predisposition, molecular groups and data analysis. https://bit.ly/3ZjdFFc

Childhood cancer genetics: A legacy of groundbreaking work drives St. Jude forward

St. Jude has a rich history of research on genetics stemming from the Pediatric Cancer Genome Project and reverberating through laboratories today.

Stjude Blogs