The risk of #infections and other complications is pronounced in the weeks after a #pediatric #BoneMarrowTransplant. Read about a new #StJude study identifying those at the highest risk, which may help protect these vulnerable #children. https://bit.ly/3PmEIx1 #StJudeResearch #ChildhoodCancer #Microbiome
Spilling their guts: patient microbiomes may hold the secret to predicting outcomes after transplant

Infections & complications after pediatric patients receive bone marrow transplants are dangerous. Discover how St. Jude microbiome research predicted risk.

Stjude Blogs
When people think of #virology, they rarely think of a week at the beach. But for the last 38 years, #StJude #avianflu hunters have traveled to #DelawareBay to collect #birdpoop which, this year, will help provide context for the ongoing #pandemic. https://bit.ly/43DRV8K #StJudeResearch #FluResearch
St. Jude avian flu hunters’ annual data collection provides context for ongoing pandemic

The ongoing avian influenza pandemic is infecting wild & domestic birds. Discover how St. Jude scientists are staying ahead of the virus & assessing its risk.

Stjude Blogs
We proudly welcome Dr. Victor J. Torres as chair of the newly formed #StJude Department of Host-Microbe Interactions, which will focus on treating and preventing #diseasecausing #infections in children. Torres, who starts in July, is actively #recruiting world-class investigators to undertake #research to learn key information about fundamental #biological, #molecular and #chemical processes of #infectiousdiseases. https://bit.ly/43Rrr3m #StJudeResearch
Victor J. Torres, Ph.D., named chair of newly formed Department of Host-Microbe Interactions at St. Jude Children’s Research Hospital

Dr. Victor J. Torres is leading a newly-formed department called the St. Jude Department of Host-Microbe Interactions, which will focus on treating and preventing disease-causing infections in children.

The #H5N1 #fluvirus poses a great unknown threat to birds and humans. For decades, #StJude #virologists have been mining #DelawareBay each year to expand their knowledge and to help thwart possible #influenza outbreaks. Learn how: http://bit.ly/3IVn1AA @emilyanthes @nytimes #StJudeResearch #FluResearch
For These Bird Flu Researchers, Work Is a Day at the Very ‘Icky’ Beach

The H5N1 virus poses “a great unknown threat” to birds and humans alike. Understanding and thwarting it begins with excrement collection.

The New York Times
Developing new treatments for #ChildhoodCancer requires creative solutions. #StJude #scientists are pushing the boundaries of what is possible by designing compounds that degrade proteins. Read about the #technology and discoveries. https://bit.ly/3NP9GNs #StJudeON #StJudeResearch
Targeted protein degradation to treat cancer

St. Jude scientists are identifying targets and designing drugs to degrade proteins implicated in hard-to-treat cancers. Learn about creating PROTACs.

Stjude Blogs
Join us in congratulating #StJude #scientist Dr. M. Madan Babu, just named a #RoyalSocietyFellow for his pioneering data science-based strategies to reveal fundamental principles in #BiologicalSystems. Discover more about his #DataDiscovery work. https://bit.ly/42I8yPN #StJudeResearch #RoyalSociety
St. Jude scientist M. Madan Babu elected to the Royal Society of London

Director of the St. Jude Center of Excellence for Data-Driven Discovery named a fellow of the 360-year-old British scientific organization.

Like comparing apples to apples, comparing similar #proteins can be challenging. #Scientists at #StJude developed a tool to help, which garnered new insights into the #ChaperoneProtein #HSP90—an essential target in #cancer. Read about their work. https://bit.ly/3LMhQVf #StJudeResearch #StructuralBiology #ChemicalBiology #DrugDiscovery
It’s the little things that count – so let’s count the little things

St. Jude scientists in the Fischer lab have published Flexr a tool for studying protein conformations, making new discoveries about HSP90. Read the blog post.

Stjude Blogs
Clinical trial improves neurocognitive outcomes for childhood craniopharyngioma

Proton therapy for craniopharyngioma had better neurocognitive than & similar survival outcomes as historical photon therapy. Read the phase 2 clinical trial.

Social determinants of health predict #CognitiveOutcomes in children. Read about the new #StJude study linking neighborhood economic hardship and cognitive outcomes in #pediatric #BrainTumor survivors treated with #RadiationTherapy. https://bit.ly/3oTMGCi #StJudeResearch #ChildhoodCancer
Study shines light on impact of environment on neurocognitive outcomes

Find how the neighborhood economic hardship index predicts baseline and long-term outcomes in pediatric brain tumor patients treated with radiation therapy.

Like a musical ensemble, a #scientific enterprise needs members who can integrate their expertise with others. Explore how #computationalist Dr. Brian Abraham conducts #ComputationalResearch as part of a larger scientific orchestra at #StJude. https://bit.ly/40Eydri #StJudeResearch #CompBio
Investigator Insights: Conducting Computational Research with Brian Abraham, PhD

St. Jude scientist Brian Abraham, PhD, conducts computational research leveraging relationships and expertise to make discoveries. Read his story.

Stjude Blogs