Hi #neuromastodon, today the latest preprint of an extremely cool, 100% Uruguay-based team has been released  

A filopodia-based dendritic mechanosensory compartment in CSF-contacting neurons

There we show that, contrary to what zebrafish has taught, these spinal cord neurons from adult mice (CSF-cN) lack cilia. Furthermore, they show multiple filopodia and are able to sense mechanical stimuli through PKD2L1. That, and other nice stuff.

If you didn't know what to read this weekend, here you have it:

https://www.biorxiv.org/content/10.64898/2026.04.09.713694v1

Hope you enjoy it.

#neuro #neurons #spinal #spinalcord #cellbiology #biology #uruguay #science #research #preprint #openaccess #microscopy #electrophysiology #neuroscience #iibce #pedeciba

These Are the Muscle Layers of Your Back

https://tube.blueben.net/w/rLVC9eG1RRmvBnHo8jTy2B

🧠 New paper by Wimalasena, Pandarinath, AuYong et al: #spinal #interneuron populations form a low-dimensional #manifold that robustly organizes step cycles.

Distinct regions of the manifold mark flexion–extension transitions, and a specific “hold region” tightly controls cycle duration. Deletions emerge as failures to enter the flexor region, giving a dynamical signature of disrupted CPG function.

🌍 https://doi.org/10.1038/s41467-025-64629-y

#Neuroscience #Locomotion #SpinalCord #PopulationDynamics #CompNeuro

#Scientists turn #bodyfat into #bone to heal #spinal #fractures

https://www.sciencedaily.com/releases/2025/11/251111005949.htm