Today in Labor History, April 16, 1943: Albert Hoffman accidentally discovered the hallucinogenic effects of LSD on this day. And forever after, working-class people could afford to take inexpensive trips without ever leaving their homes. Hoffman, who was a chemist at the Sandoz Laboratories in Basel, first synthesized LSD in1938. He set the drug aside for five years, before accidentally ingesting some on this date in 1943. Three days later, April 19, he deliberately ingested 250 micrograms of LSD, believing this tiny dosage would be barely, if at all, noticeable. Turns out, this is a pretty strong dose. He watched people morph into weird creatures, office furniture become “alive,” and he felt like he was possessed by otherworldly forces. He tried to ride his bicycle home, to safety, but things just got weirder. April 19 is now known as “Bicycle Day,” in commemoration of the first deliberate LSD trip.

He also named and synthesized the principal psychedelic chemicals psilocybin and psilocin, found in psilocybin mushrooms. And in 1929 he discovered the structure of chitin, the polysaccharide found in the cell walls of fungi, and in the shells of arthropods, like shrimp, crabs, spiders and insects, and in the beaks and radula of mollusks, like snails and octopi. He wrote over 100 scientific articles in his lifetime, and the book: LSD: Mein Sorgenkind (LSD: My Problem Child). In 1962, he traveled to Mexico to obtain samples of Salvia divinorum, but was never able to isolate the psychoactive alkaloids. He also discovered a close relative of LSD in Morning Glory seeds. In an interview just before his 100th birthday, Hofmann called LSD "medicine for the soul." Angered by its worldwide legal bans, he said argued that it had been used successfully for ten years in psychoanalysis prior to its U.S. prohibition. He also criticized its “misuse” by the counterculture of the 1960s.

#workingclass #LaborHistory #LSD #psychedelic #AlbertHoffman #chemistry #mushrooms #psilocybin #sandoz #salvia

Africa: Magic Mushrooms - New African Species Sheds Light On the History of the Famous Fungus: [The Conversation Africa] "Magic mushrooms" are consumed recreationally and for medicinal purposes around the world. These fungi gained their fame as "magic" because they produce chemical compounds (called psilocybin and psilocin) which have psychedelic effects. http://newsfeed.facilit8.network/TRyYSF #MagicMushrooms #Psychedelic #Psilocybin #Fungi #MedicinalMushrooms
Psychedelics helped him deal with terminal illness anxiety, but getting them was a long, strange trip
Five years after Pete Pearson, 75, was diagnosed with a terminal lung condition, he was experiencing debilitating anxiety and depression known as "end-of-life distress." He wanted to try psilocybin — commonly known as magic mushrooms — to see if it helped. After a lengthy and futile attempt to gain acce...
https://www.cbc.ca/radio/whitecoat/psychedelic-treatment-health-canada-9.7151538?cmp=rss
Despite their distinct chemical compositions, various psychedelic compounds—including psilocybin, LSD, mescaline, DMT, and ayahuasca—produce a unified, common pattern of brain activity.
#Neuroscience #Psychiatry #Biomedical #Pharmaceutical #psilocybin #sflorg
https://www.sflorg.com/2026/04/ns04072601.html
Largest-ever study of psychedelics could help advance their use in treating mental health disorders

Different psychedelics have shown benefits for some mental health conditions

Psychedelic-assisted pharmacotherapy: clinical applications and regulatory considerations - PubMed

Psychedelic-assisted therapies are unlikely to follow a conventional prescription model and instead require specialist-delivered, psychotherapy-integrated care under appropriate regulatory and ethical safeguards. While late-stage trials support their potential in high-need populations, unresolved ch …

PubMed
Psychedelics helped Mooretown man deal with terminal illness anxiety, but it was a long, strange trip
Five years after Pete Pearson, 75, was diagnosed with a terminal lung condition, he was experiencing debilitating anxiety and depression known as "end-of-life distress." He wanted to try psilocybin — commonly known as magic mushrooms — to see if it helped. After a lengthy and futile attempt to gain acce...
https://www.cbc.ca/radio/whitecoat/psychedelic-treatment-health-canada-9.7151538?cmp=rss
Psychedelics helped him deal with terminal illness anxiety, but getting them was a long, strange trip
Five years after Pete Pearson, 75, was diagnosed with a terminal lung condition, he was experiencing debilitating anxiety and depression known as "end-of-life distress." He wanted to try psilocybin — commonly known as magic mushrooms — to see if it helped. After a lengthy and futile attempt to gain acce...
https://www.cbc.ca/radio/whitecoat/psychedelic-treatment-health-canada-9.7151538?cmp=rss

The people who are voted in for governance should be obliged to undergo a rigorous psilocybin-therapy before going into function. Maybe it should even be strongly suggested for every other human living on this planet. Let's see what happens.

#psilocybin #psychedelics #wellbeing #psychology

https://www.psypost.org/psilocybin-triggers-lasting-changes-in-personal-values-for-healthy-volunteers/

Can a psychedelic journey change what you value most?

A recent trial involving healthy volunteers demonstrates that a single dose of psilocybin can prompt lasting changes in personal values, increasing self-acceptance and appreciation for life through acute feelings of spiritual euphoria and profound unity.

PsyPost Psychology News
Magic mushroom-infused products appear in Colorado gas stations – what public health officials want consumers to know

Hallucinogenic chocolate bars were removed from six Denver-area gas stations.

The Conversation

Under 2024 gjorde Tullverket 61 beslag av narkotisk svamp. 2025 ökade antalet till hela 386 beslag. I Tullverkets utredningar framgår att många beställer svamp på nätet för att självmedicinera mot bland annat depression.

https://blog.zaramis.se/2026/04/04/okade-beslag-av-narkotiska-svampar/