PLOS BiologyAug 4, 2023
Interaction between components of #MicrotubuleOrganizingCenters & #NuclearPores (Bfa1/Bub2 & Nup159) that facilitates autophagic degradation of a pool of #nucleoporin complexes and may favor specific elimination in the daughter cell @FMC_lab #PLOSBiology https://plos.io/45gNH7q
Characterization of a novel interaction of the Nup159 nucleoporin with asymmetrically localized spindle pole body proteins and its link with autophagy

This study reveals a new link between microtubule-organizing centers and nuclear pores in budding yeast by unveiling an interaction between components of these structures (Bfa1/Bub2 and Nup159) that facilitate the selective autophagic degradation of a pool of nucleoporin complexes and might favor their specific elimination in the daughter cell.

Julien DelpierreNov 8, 2022
I came across this #microscopy paper. https://www.nature.com/articles/s41587-022-01519-4
"By blue-shifting the #STED beam and separating #fluorophores by on/off switching, individual fluorophores bound to a #DNA strand are localized with σ = 4.7 Å, corresponding to a fraction of the fluorophore size, with only 2,000 detected #photons ."
This image showing resolution below the size of the fluorophore leaves me speechless.
The paper features images of #DNAorigami, #NuclearPores, synaptic #Vesicles, #ECM (#laminin) and #vilmentin
MINSTED nanoscopy enters the Ångström localization range - Nature Biotechnology

Sub-nanometer localization precision is achieved with all-optical microscopy.

Nature