Education & KnowledgeIs this God’s protein?
PeerTube
Atheism ActuallyNext time a Christian brings up the cruciform *illustrative* structure of laminin, show them that of the (extremely toxic) methanol. 💁🧑🏫🧑🔬
#chemistry #apologetics #God #Jesus #Crucifixion #laminin #cherryPicking
PLOS BiologyHow is cell basal geometry is regulated during epithelial #morphogenesis? @PichaudLab &co show that a pathway involving #laminin & #integrin adhesion coordinates remodelling of #EpithelialCell shape by patterning their basement membrane #PLOSBiology https://plos.io/4e457co
A dystroglycan–laminin–integrin axis coordinates cell shape remodeling in the developing Drosophila retina
Cell shape remodeling is a main driver of epithelial tissue morphogenesis, but how cell basal geometry is regulated remains unclear. This work identifies a novel morphogenetic pathway involving laminin and integrin adhesion that coordinates the remodelling of epithelial cell shape by patterning their basement membrane.
preLights“This #preprint has provided me with a fresh outlook on the significance of the extracellular matrix in tissue morphogenesis and organ development.”
First preLights post by Bhaval Parmar covering work from Cecília G. De Magalhães & team
#preLight 👉 https://prelights.biologists.com/highlights/lens-placode-modulates-extracellular-matrix-formation-during-early-eye-development-v2/
CellBioNews#Predator_prey defense mechanisms could unlock key to marine #biofuel production.
#Aplysia #kelp #phaeophyta #laminin #akuBGL #enzyme
https://phys.org/news/2023-10-predator-prey-defense-mechanisms-key-marine.html
Biology OpenRana Ramadan and colleagues show that extracellular matrix #remodelling plays a role in the maintenance of #intestinal stem cells and crypt morphology both during #development and in the adult mouse #gut:
#StemCells #ECM #Laminin #Science #BiologyOpen #Biology #AcademicMastodon
Journal of Cell ScienceKatajisto &co show that laminin matrix adhesion regulates basal mammary epithelial cell identity: https://journals.biologists.com/jcs/article/135/23/jcs260232/285829/Laminin-matrix-adhesion-regulates-basal-mammary
#cellbiology #research #sciencemastodon #science #laminin #basementmembrane
#cellbiology #research #sciencemastodon #science #laminin #basementmembrane
Laminin matrix adhesion regulates basal mammary epithelial cell identity
Summary: Basal mammary epithelial cells exhibit remarkable plasticity and self-renewal activity. Adhesion of basal cells to laminin α5-containing matrix controls their function by directing them towards a luminal cell fate.
Yale School of MedicineIn a new study from #Yale Cancer Center, Don Nguyen, PhD, says #laminin produced by blood vessels in the brain may help #cancer cells form #metastasis and evade treatment. Researchers found residual #tumor cells remain even with good drug penetration. #medmastodon
https://medicine.yale.edu/news-article/yale-cancer-center-study-characterizes-link-between-drug-resistance-and-central-nervous-system-relapse/
https://medicine.yale.edu/news-article/yale-cancer-center-study-characterizes-link-between-drug-resistance-and-central-nervous-system-relapse/
Julien DelpierreI came across this #microscopy paper. https://www.nature.com/articles/s41587-022-01519-4
"By blue-shifting the #STED beam and separating #fluorophores by on/off switching, individual fluorophores bound to a #DNA strand are localized with σ = 4.7 Å, corresponding to a fraction of the fluorophore size, with only 2,000 detected #photons ."
This image showing resolution below the size of the fluorophore leaves me speechless.
The paper features images of #DNAorigami, #NuclearPores, synaptic #Vesicles, #ECM (#laminin) and #vilmentin
"By blue-shifting the #STED beam and separating #fluorophores by on/off switching, individual fluorophores bound to a #DNA strand are localized with σ = 4.7 Å, corresponding to a fraction of the fluorophore size, with only 2,000 detected #photons ."
This image showing resolution below the size of the fluorophore leaves me speechless.
The paper features images of #DNAorigami, #NuclearPores, synaptic #Vesicles, #ECM (#laminin) and #vilmentin
