🧬 "Il DNA origami ci apre le porte a vaccini futuristi post-mRNA. Benvenuti nell'era della medicina personalizzata 2.0!" #DNAOrigami #FutureOfVaccines
🔗 https://www.tomshw.it/scienze/vaccini-a-dna-origami-il-salto-oltre-lmrna-2026-03-18
🧬 "Il DNA origami ci apre le porte a vaccini futuristi post-mRNA. Benvenuti nell'era della medicina personalizzata 2.0!" #DNAOrigami #FutureOfVaccines
🔗 https://www.tomshw.it/scienze/vaccini-a-dna-origami-il-salto-oltre-lmrna-2026-03-18
18-Sep-2024
#Nanotechnology: #DNA origami with cargo function
https://www.eurekalert.org/news-releases/1058402 #science #nanoworld #DNAorigami
scientists from the Karolinska Institutet in Sweden have developed tiny robots, or nanorobots, capable of specifically targeting and killing cancer cells. These nanorobots activate the cells' 'death receptors' to help shrink tumors.
#CancerResearch #MedicalBreakthrough #Nanotechnology #HealthInnovation #DNAOrigami #CancerTreatment #MedicalScience #TechNews
15-MAR-2024
#DNAorigami-based #vaccines toward safe and highly-effective precision cancer #immunotherapy
Broadly applicable vaccine platform enables enhanced anti-tumor responses through nanometer-precise spacing of adjuvant molecules and a variety of antigens
https://www.eurekalert.org/news-releases/1037728
I love a bit of #DNAnanotechnology and have covered that field for >25 years now but I would be worried about using it in a biological context where sequences might discover unintended meaning. #science
<p>Researchers at the Wyss Institute at Harvard University, <a href="https://www.dana-farber.org/">Dana-Farber Cancer Institute</a> (DFCI), <a href="https://hms.harvard.edu/">Harvard Medical School</a>(HMS), and <a href="https://www.nst.re.kr/eng/contents.do?key=154">Korea Institute of Science and Technology</a> (KIST) have created a DNA origami platform called <a href="https://wyss.harvard.edu/technology/dorivac-boosting-antigen-specific-immune-responses-with-dna-origami-based-vaccines/">DoriVac</a>, whose core component is a self-assembling square block-shaped nanostructure. To one face of the square block, defined numbers of adjuvant molecules can be attached in highly tunable, nanoprecise patterns, while the opposite face can bind tumor antigens. The study found that molecules of an adjuvant molecule spaced exactly 3.5 nanometers apart from each other resulted in the most beneficial stimulation of APCs that induced a highly-desirable profile of T cells, including those that kill cancer cells (cytotoxic T cells), those that cause beneficial inflammation (Th-1 polarized T cells), and those that provide a long-term immune memory of the tumor (memory T cells). DoriVac vaccines enabled tumor-bearing mice to better control the growth of tumors and to survive significantly longer than control mice.</p>
Ein Team um @hendrik_dietz, @cees_dekker & @aksimentievlab bastelt aus #DNAOrigami eine biologische #Nano-Turbine, die wie ein Motorprotein elektrochemische Energie in mechanische Arbeit umwandelt …
— Andrea Pitzschke erklärt uns die Details: 👉 https://www.laborjournal.de/editorials/2872.php
26-Oct-2023
DNA Origami nanoturbine sets new horizon for nanomotors
https://www.eurekalert.org/news-releases/1005774 #science #nanoworld #nanotechnology #DNAorigami
<p style="text-align:justify">A collaborative team of researchers led by prof. Cees Dekker at TU Delft, in partnership with international colleagues, introduces a pioneering breakthrough in the world of nanomotors – the DNA origami nanoturbine. This nanoscale device could represent a paradigm shift, harnessing power from ion gradients or electrical potential across a solid-state nanopore to drive the turbine into mechanical rotations. The core of this pioneering discovery is the design, construction, and driven motion of a ’DNA origami’ turbine, which features three chiral blades, all within a minuscule 25-nanometer frame, operating in a solid-state nanopore. By ingeniously designing two chiral turbines, researchers now have the capability to dictate the direction of rotation, clockwise or anticlockwise. Their research findings have been published in Nature Nanotechnology on October 26.</p> <p style="text-align:justify">Dr. Xin Shi: "We have created our own nanoturbines capable of driving our desired processes”</p>
Controlling insulin activity in cells with ‘DNA origami’ | 25 October 2023