Characterization of a novel interaction of the Nup159 nucleoporin with asymmetrically localized spindle pole body proteins and its link with autophagy

This study reveals a new link between microtubule-organizing centers and nuclear pores in budding yeast by unveiling an interaction between components of these structures (Bfa1/Bub2 and Nup159) that facilitate the selective autophagic degradation of a pool of nucleoporin complexes and might favor their specific elimination in the daughter cell.