#Neoadjuvant treatment with the #immunotherapy drug pembrolizumab significantly shrinks or eliminates #tumors in patients with desmoplastic #melanoma , a rare and aggressive form of skin #cancer
#Oncology #Immunology #Dermatology #sflorg
https://www.sflorg.com/2026/01/ongy01292601.html
Immunotherapy before surgery helps shrink tumors in patients with desmoplastic melanoma

New approach spares patients from more disfiguring surgeries or additional treatments

Patients with soft-tissue #sarcoma treated with #neoadjuvant, or pre-surgical, #immunotherapy had very little residual #tumor at the time of surgery and promising long-term survival
#Medical #Cancer #sflorg
https://www.sflorg.com/2024/02/med02132301.html
Immunotherapy before surgery leads to promising long-term survival in sarcoma patients

MD Anderson-led Phase II trial suggests neoadjuvant immunotherapy is safe and may be an effective option for patients with soft-tissue sarcomas

New findings from the #NEOSTAR trial provide further support for #neoadjuvant #immunotherapy-based treatment as an approach to reduce viable #tumor at #surgery and to improve outcomes in #NSCLC. The combination also was associated with an increase in #immune #cell infiltration and a favorable #gut #microbiome composition.
#Medical #Biology #Microbiology #sflorg
https://www.sflorg.com/2023/03/med03162303.html
Dual immunotherapy plus chemotherapy before surgery improves patient outcomes in operable lung cancer

neoadjuvant immunotherapy-based treatment as an approach to reduce viable tumor at surgery

#pancreaticcancer or #PancreaticDuctalAdenoCarcinoma is a still an extreme challenge in #Oncology. New insights on #adjuvantchemotherapy after resection and prior #neoadjuvant #chemotherapy suggest a new direction, but many questions remain...what type of chemotherapy or what type of patient is able to go through this treatment?
https://ja.ma/3iKFwNN
Adjuvant Chemotherapy in Patients With Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy

This cohort study of data from the National Cancer Database on patients with pancreatic adenocarcinoma who received neoadjuvant chemotherapy compares overall survival between those who received adjuvant chemotherapy and those who did not.