Primer humano vacunado contra el cáncer en Rusia: ¿realmente funciona? #Neoonkovak #Cancer #Melanoma #VacunaContraElCancer #ARNmensajero #Oncologia #Inmunoterapia #InvestigacionMedica #Ciencia #Salud #Rusia #felizlunes #15dejunio
https://donporque.com/primer-humano-vacunado-contra-el-cancer-en-rusia/
🐁 Studium nádorových onemocnění má problém – rakovina je dle statistik u lidí ČASTĚJŠÍ VE STÁŘÍ, jenže většina pokusů na myšácích se dělá NA MLADÝCH ZVÍŘATECH. To je trochu jako testovat důchodovou reformu na maturantech – technicky data sice máte, ale v praxi se moc nepropisují do reality… 😅
Výzkumníci z Fox Chase Cancer Center fčil zjistili, že melanom se u myší nejméně šířil u mladých zvířat, NEJVÍC u myší STŘEDNÍHO věku a pak zase méně U VELMI STARÝCH. Klíčem mohou dle nich být tzv. gamma delta T buňky, které pomáhají držet nádorové buňky v klidovém stavu. 🧐
Prečo? Ve středním věku těchto buněk UBÝVALO a nádory je navíc dokázaly DÁLE OSLABOVAT. Když vědátoři ochranné signály obnovili, šíření melanomu u středně starých myší KLESLO. Budiž to pro mnohé z nás připomínka chodit pravidelně za kožní – a pro vědátory notifikace, že jevy našeho těla jsou zas o něco složitější, než jsme doufali… 🫠
Uno studio condotto su oltre 470.000 persone ha rilevato che chi utilizza creme solari corre un rischio notevolmente maggiore di melanoma, carcinoma basocellulare e carcinoma squamocellulare, anche…
Last week research was presented halving melanoma recurrence risk via a personal vaccine https://www.nbcnews.com/health/cancer/personalized-vaccine-melanoma-cut-risk-cancer-returning-five-years-rcna347424
The cited rates even in the control group are themselves a fairly recent miracle, including work by Georgina Long and Richard Scolyer. Richard died yesterday of glioblastoma, following self-experimentation, both of immunotherapy and of a personal vaccine. This is now in early clinical trials on others.
I hope he had a chance to learn of the Moderna and Merck result on melanoma in his last weeks.
"A #cancer vaccine,⚡using the same core #mRNA technology as the #COVID vaccine, has shown an almost 50% reduction in the risk of #melanoma recurrence or death when combined with immunotherapy...
Global cancer care is approaching a new breaking pt.
I was honored to be a part of the latest The Lancet Oncol Comm that projects a nearly 100M worker shortfall by 2050, wth the greatest burden falling on LMICs..."
-Dr C Young
#Health #Vaccines #HHS #RFKJr #Kakistocracy #USPol
https://www.npr.org/2026/06/01/nx-s1-5827041/cancer-vaccine-mrna-melanoma
Study finds melanoma metastasis peaks in middle age due to immune system changes
📰 Original title: Why cancer spreads more in middle age than in old age
🤖 IA: It's not clickbait ✅
👥 Users: It's not clickbait ✅
Recent research from scientists studying melanoma suggests that cancer does not spread in a simple, linear way with aging. Instead, tumor progression appears to vary significantly depending on life stage. In mouse models, researchers observed that melanoma spread was lowest in young animals, increased sharply in middle-aged mice, and then decreased again in very old mice. This unexpected pattern challenges the traditional assumption that cancer aggressiveness steadily increases with age. A key factor behind this pattern appears to be the immune system, particularly a specialized group of immune cells known as gamma delta (γδ) T cells. These cells help suppress tumor growth and keep cancer cells in a dormant state. The study found that both young and very old mice had higher levels of these protective immune cells, which helped limit cancer spread. In contrast, middle-aged mice had significantly fewer γδ T cells, making them more vulnerable to metastatic disease. Researchers also discovered that melanoma cells may actively weaken immune defenses as the host ages. In middle age, cancer appears to release signals that exhaust or suppress γδ T cells, allowing tumors to become more aggressive and spread to organs such as the lungs and liver. When scientists experimentally removed γδ T cells from young and aged mice, cancer spread increased, confirming their protective role. Interestingly, blocking the tumor-induced immune suppression in middle-aged mice restored some immune function and reduced metastasis, although the effect did not fully replicate in the youngest or oldest groups. The findings highlight the importance of studying cancer in aged animal models, as most current research relies on young mice that do not fully represent real-world aging. Overall, the study suggests that immune system dynamics across the lifespan may explain why cancer risk and severity can fluctuate with age rather than increase uniformly.
Study finds melanoma metastasis peaks in middle age due to immune system changes
📰 Original title: Why cancer spreads more in middle age than in old age
🤖 IA: It's not clickbait ✅
👥 Users: It's not clickbait ✅
Recent research from scientists studying melanoma suggests that cancer does not spread in a simple, linear way with aging. Instead, tumor progression appears to vary significantly depending on life stage. In mouse models, researchers observed that melanoma spread was lowest in young animals, increased sharply in middle-aged mice, and then decreased again in very old mice. This unexpected pattern challenges the traditional assumption that cancer aggressiveness steadily increases with age. A key factor behind this pattern appears to be the immune system, particularly a specialized group of immune cells known as gamma delta (γδ) T cells. These cells help suppress tumor growth and keep cancer cells in a dormant state. The study found that both young and very old mice had higher levels of these protective immune cells, which helped limit cancer spread. In contrast, middle-aged mice had significantly fewer γδ T cells, making them more vulnerable to metastatic disease. Researchers also discovered that melanoma cells may actively weaken immune defenses as the host ages. In middle age, cancer appears to release signals that exhaust or suppress γδ T cells, allowing tumors to become more aggressive and spread to organs such as the lungs and liver. When scientists experimentally removed γδ T cells from young and aged mice, cancer spread increased, confirming their protective role. Interestingly, blocking the tumor-induced immune suppression in middle-aged mice restored some immune function and reduced metastasis, although the effect did not fully replicate in the youngest or oldest groups. The findings highlight the importance of studying cancer in aged animal models, as most current research relies on young mice that do not fully represent real-world aging. Overall, the study suggests that immune system dynamics across the lifespan may explain why cancer risk and severity can fluctuate with age rather than increase uniformly.
Impulsan campaña para prevenir y detectar melanoma a tiempo
La campaña Objetivo Cero Melanoma 2026 por Cantabria Labs pone el foco en la autoexploración de lunares mediante la regla ABCDE.
Por Deyanira Vázquez | Reportera
Un lunar que cambia, una mancha que antes no estaba, una herida que no termina de cicatrizar o una lesión que pasa desapercibida durante meses pueden ser señales de alerta. Con motivo del Día Mundial del Melanoma.
Cantabria Labs impulsa una nueva edición de Objetivo Cero Melanoma 2026, una campaña de concientización y prevención que vuelve a poner el foco en un gesto sencillo, rápido y decisivo: revisar los lunares con la regla ABCDE y consultar a un dermatólogo ante cualquier cambio sospechoso.
La campaña cuenta con el apoyo de Rafa Nadal, embajador de Cantabria Labs, y con la participación del Dr. Juan José Andrés Lencina, dermatólogo y Director Médico de Cantabria Labs; la Dra. Natalia Jiménez, dermatóloga en el Hospital Universitario Ramón y Cajal y en Grupo Pedro Jaén; y la Dra. Lourdes Navarro, dermatóloga y portavoz de la Fundación Piel Sana.
Los especialistas coinciden en un mensaje central: revisar la piel, protegerla del sol y consultar al dermatólogo ante cualquier cambio sospechoso son gestos clave para favorecer el diagnóstico precoz del melanoma. –sn–
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