Study identifies mitochondrial dysfunction as cause of long-COVID fatigue

Researchers from Amsterdam UMC and Vrije Universiteit Amsterdam (VU) have discovered that the persistent fatigue in patients with long-COVID has a biological cause, namely mitochondria in muscle cells that produce less energy than in healthy patients.

Scientists map the distribution of carnitine in muscle cells

Researchers from Tokyo Metropolitan University have developed a way of mapping the distribution of carnitine in skeletal muscle cells. Carnitine is a compound that helps transport fatty acids and reduce metabolic byproducts. They discovered that slow-type muscle fibers contained the most, and that activity promptly led to rises in acetylcarnitine, a product of the immediate response of carnitine contained in the cell. Their technique promises new insights into how muscle cells work.

The cartographer of life

Muscle cells are very good at repairing damage. But if this fails, stem cells step in to regenerate the tissue. Carmen Birchmeier investigates the molecular signaling pathways that underlie these and other vital mechanisms.

When smooth muscle cells lack strength | University of Tübingen