Amelia Cervera 🧬Aug 29, 2025

Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome.

#MobileGeneticElements #MGEs #ExtrachromosomalElements #Plasmids #Microbiome #EnvironmentalStress

https://www.nature.com/articles/s41467-025-62406-5

Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome - Nature Communications

This study identified prevalent giant extrachromosomal elements from the human oral microbiome. The genetic and ecological analysis provides insight on the potential contribution of this element in adaptation against multiple oral environmental stressors.

Nature
Axel ViselAug 23, 2023

Day 3 of #JGI2023:

#Metabolites, #Viruses, #MobileGeneticElements, #Plants and more!

https://usermeeting.jgi.doe.gov/agenda/

@LBNLBioSci #JGI #Genomics

JGI Genomics of Energy and Environment Meeting Agenda

Check out the agenda for the Annual JGI Genomics of Energy & Environment Meeting

JGI Annual User Meeting
Michael BrockhurstFeb 16, 2023

Exciting new paper in @PLOSBiology — we show that plasmids use translational global regulators to rewire host cells including expression of key ecological traits, like metabolism and motility, whilst also boosting horizontal transmission of the plasmid

This was a big collaborative effort with colleagues at John Innes Centre, Birmingham, Sheffield & Liverpool

#plasmid #HGT #MobileGeneticElements

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001988

Plasmids manipulate bacterial behaviour through translational regulatory crosstalk

Plasmids contain homologs of bacterial signaling proteins and use them to manipulate host cells to their benefit. This study describes a widespread plasmid-borne translational regulator that subverts ecological traits in soil bacteria, inducing community organization and promoting plasmid transmission.

Melinda Ashcroft (PhD)Nov 3, 2022
Getting in on the #introduction bandwagon! Hi all, I'm a purely computational Postdoctoral Research Fellow at Monash Uni. My research passions are #MicrobialGenomics, #AMR, #Virulence, #MobileGeneticElements & #Epigenomics. I'm most interested in bacterial #InfectiousDiseases, with clinical and/or public health focuses. My research to date has focused on Escherichia coli, Neisseria gonorrhoeae and Klebsiella species. Have a lot of experience with NGS data & #phylogenomics. Love research! 🦠