Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome.

#MobileGeneticElements #MGEs #ExtrachromosomalElements #Plasmids #Microbiome #EnvironmentalStress

https://www.nature.com/articles/s41467-025-62406-5

Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome - Nature Communications

This study identified prevalent giant extrachromosomal elements from the human oral microbiome. The genetic and ecological analysis provides insight on the potential contribution of this element in adaptation against multiple oral environmental stressors.

Nature