These new studies are relevant for understanding and explaining female psycho-biological trauma responses. Although men experience more trauma, women are twice as likely to develop posttraumatic stress disorder. The study suggests that fluctuations in the female hormone estradiol are connected to heightened sensitivity and amygdala activation.
https://news.emory.edu/stories/2026/01/hs_bhc_stevens_estradiol/story.html

Hormone estradiol shapes women’s brain responses to threat after trauma, Emory study finds | Emory University | Atlanta GA
An Emory study finds the ovarian hormone estradiol influences women’s brain responses to threat, but traumatic stress can disrupt this regulation, which helps explain women’s increased risk for PTSD.