kari hoffmanDec 2, 2023
First glance: Bringing together some important concepts relevant for neural representation #memory #hippocampus and internally generated sequences #MemoryReplay @cogneurophys https://www.nature.com/articles/s41583-023-00763-0
The generative grammar of the brain: a critique of internally generated representations - Nature Reviews Neuroscience

Neurobiological organizational principles suggest that a generative grammar exists in the brain. In this Perspective, Dragoi proposes how neural grammar enables specific experience-independent, internally generated patterns of activity acquired via spontaneous generative combination of pre-existing sequential motifs to support internally generated representations of experience in the hippocampus.

Nature
Show threadkari hoffmanJul 4, 2023

@elduvelle @LMPrida @biorxivpreprint @cogneurophys I’m stoked that it worked out so well! The assessment followed closely the methods in Navas-Olive CNN paper https://elifesciences.org/articles/77772 using F1 (balanced accuracy) to reflect both precision and recall (i.e. sensitivity). So both FN and FPs count against the score, equally. The human raters were around .7 and the monkey data started at ~.5 and reached ~.6 (same as mouse levels!) after retraining. A pleasant surprise, given visible differences in the SWR phenotype between rodent and primate clades!

I think Andrea will post more details soon, but meanwhile, some relevant keywords for interested folks (can you think of others we should use?)

#neuroscience #MemoryReplay #learningandmemory #hippocampus #ripples #SWR #replay #cnn #lstm #openscience #hackathon #oscillations

Deep learning-based feature extraction for prediction and interpretation of sharp-wave ripples in the rodent hippocampus

A new method is described to identify sharp-wave ripples from the rodent hippocampus with deep learning techniques, which may help to identify and characterize previously undetected physiological events.

eLife
Simon KernDec 18, 2022

New instance, new #introduction :) I moved to neuromatch.social as it seems to match my interests more closely.

I'm a PhD candidate working at the intersection of #sleep, #memory and #MachineLearning. I'm currently on a mission to uncover #MemoryReplay and #MemoryReactivation in humans using #MEG data. Besides that I'm a #python enthusiast, #OpenSource advocate and I think #OpenScience is the proper way to do science. I'm doing all of that at the Central Institute of Mental Health with @GordonFeld

Simon KernNov 13, 2022

Here's my #introduction :)

I'm a PhD candidate working at the intersection of #sleep, #memory and #MachineLearning. I'm currently on a mission to uncover #MemoryReplay and #MemoryReactivation in humans using #MEG data. Besides that I'm a #python enthusiast, #OpenSource advocate and I think #OpenScience is the proper way to do science. I'm doing all of that at the Central Institute of Mental Health with @GordonFeld