Neurogenetics Leicester

@NeurogeneticsLeicester@biologists.social
97 Followers
157 Following
127 Posts
Research groups at University of Leicester, studying #genetic, #epigenetic and #evolutionary mechanisms underlying #biologicalclocks, #development, #neurodegeneration, #ageing and #sleep across animal taxa
On my way home from London Fly Meeting, feeling very proud of Leicester Neurogenetics @NeurogeneticsLeicester PhD Emily Sample who gave a very good talk and gather a lot of feedback, also had a couple celebrations pints at Sommer House Cafe! Also catching up with UCL gangs! Blissful feeling #drosophila rocks! #genetics

#FightForSight Funded #PhD project to work on #zebrafish model of infantile nystagmus! at
@NeurogeneticsLeicester

https://www.findaphd.com/phds/project/exploring-therapeutic-interventions-for-infantile-nystagmus/?p184343

please boost and spread the words! and contact Dr Mervyn Thomas mt350@le.ac.uk directly for this exciting opportunity!
#neuroscience

We’re capturing the energy of #biologists100 by walking around with a polaroid frame, highlighting the incredible early-career researchers at the conference! ✨

We’re kicking things off with @JontyTownson, the #preLights conference reporter, who is uncovering the stories behind the #preprints being presented.

If you're at the meeting, please come say hi + get your snapshot! 📸

#community #selfies #imaging #organelles

Pinched this photo from Seema Grewal on bsky. Very enjoyable social with the @J_Cell_Sci crew last night around the Albert Dock. #Biologists100
Metabolism: Insulin control in fruit flies

Investigating how the production of insulin is regulated in fruit flies reveals surprising insights that may help to better understand how this process unfolds in humans.

eLife

#circadian #sleep #lighting

call for paper

"special issue of ‘Neurobiology of Sleep and Circadian Rhythms’ on all aspects of circadian lighting, from the fundamental neuroscience on the mechanisms mediating responses to light, to studies on circadian rhythm and sleep disruption by the light environment and translational studies optimizing lighting conditions. This may include original articles as well as reviews providing new perspectives on this field"

https://www.sciencedirect.com/special-issue/319333/circadian-lighting
@bioclocksuk

We are excited to welcome everyone to Liverpool for this week’s Biologists @ 100 conference. We will be posting across our social media channels all week and you can follow the action at #biologists100

Excessive olfactory memory in the insomniac fruit fly mutant:

"we report our surprising findings that insomniac (inc) Drosophila short sleep mutants, which lack a crucial adaptor protein for the autism-associated Cullin-3 ubiquitin ligase, exhibited excessive olfactory memory."

And then the paper goes on to inquire into the molecular basis of this, and reports:

"find that a mild attenuation of Protein Kinase A (PKA) signaling specifically rescued the sleep and longevity phenotypes of inc mutants. Surprisingly, this mild PKA signaling reduction further boosted the excessive memory in inc mutants, coupled with further exaggerated mushroom body overgrowth phenotypes."

From:
"Cognitive hyperplasticity drives insomnia", by Huang et al. (Sigrist lab) 2024
https://www.biorxiv.org/content/10.1101/2024.07.16.603670v1.full

#Drosophila #neuroscience #LearningAndMemory

Delighted to see our work on #diatom motility published in @pnas.org !🎉 doi.org/10.1073/pnas... These abundant single-celled algae are responsible for a significant portion of the air we breathe yet often overlooked. Here we show how how diatom (raphe) shape impacts their gliding function... 1/3
Bluesky

Bluesky Social

Given the choice, mice spend less than 1 hour a day in bright environments.

SWC Seminar speaker Dr Stuart Peirson (University of Oxford) discusses circadian rhythms and naturalistic behaviour in our latest Q&A.

Read more ⬇️

https://www.sainsburywellcome.org/web/qa/dawn-dusk-science-behind-light-and-circadian-rhythms

From dawn to dusk: the science behind light and circadian rhythms | Sainsbury Wellcome Centre