The #circadian clock & cellular #metabolism are tightly coupled. This Primer explores a @plosbiology.org study showing how #glucose metabolism changes during the day in #Drosophila and how it is disrupted in clock & sleep mutants. Paper: https://plos.io/3Olm1M1 Primer: https://plos.io/4sUov2g

📰 "Circadian clock gates diurnal glucose utilization"
https://doi.org/doi:10.1371/journal.pbio.3003743
https://pubmed.ncbi.nlm.nih.gov/41996297/
#Circadian
#Metabolism #Drosophila #Sleep

📰 "Glucose is dynamically regulated by time of day in humans and Drosophila"
https://doi.org/doi:10.1371/journal.pbio.3003717
https://pubmed.ncbi.nlm.nih.gov/41989995/
#Circadian
#Metabolism #Drosophila

How do #circadian clocks regulate glucose processing? By integrating human metabolite profiling with isotope-tracing in #Drosophila, this study defines daily rhythms in #glucose utilization that are influenced by circadian timing @PLOSBiology https://plos.io/3Olm1M1

Does the mammalian #circadian clock manage to temperature-compensate during deep #hypothermia? This study shows that mice maintain circadian rhythms during a #hibernation -like hypothermic state, and that this is supported by systemic regulatory mechanisms @PLOSBiology https://plos.io/4tW1pJt

📰 "The curious case of CCHamide1: a role for CCHamide1 in sleep, metabolism and fitness in Drosophila melanogaster"
https://doi.org/doi:10.1093/genetics/iyag096
https://pubmed.ncbi.nlm.nih.gov/41968725/
#DrosophilaMelanogaster
#Drosophila #Metabolism #Circadian
#Sleep

📰 "Drosophila RSK: A Pivotal Regulator of Circadian Plasticity at the Neuronal and Behavioral Level"
https://doi.org/doi:10.1177/07487304261434715
https://pubmed.ncbi.nlm.nih.gov/41966995/
#Circadian
#Drosophila #Behaviour

📰 "Cell-type-specific circadian and light-responsive transcriptional dynamics in adult Drosophila neurons"
https://www.biorxiv.org/content/10.64898/2026.04.07.717038v1?rss=1
#Circadian
#Drosophila #Behaviour #Adult

📰 "Circadian Rhythms Time Seizure Severity in Drosophila"
https://doi.org/doi:10.1177/07487304261428337
https://pubmed.ncbi.nlm.nih.gov/41958013/
#DrosophilaMelanogaster
#Drosophila #Circadian