Mit KI gegen Viren: Wie neue Technologien die Impfstoffforschung voranbringen

Wissenschaftler nutzen Künstliche Intelligenz, um Proteinstrukturen von Viren zu entschlüsseln - Grundlage für zukünftige Impfstoffe.

Tino Eberl

#KINutzen

Ein Forscherteam hat mithilfe von Künstlicher Intelligenz die #Proteinstrukturen der #Flaviviridae-#Virenfamilie untersucht, zu der u.a. #HepatitisC, #Zika und #Dengue gehören. Dadurch wurden neue Glykoproteine entdeckt, die entscheidend für das Eindringen der #Viren in #Wirtszellen sind. Besonders bei Hepatitis C wurden neue #Eintrittsmechanismen entschlüsselt, was die Entwicklung von Impfstoffen erleichtern könnte.

#KünstlicheIntelligenz #virologie

https://tino-eberl.de/nutzen-kuenstlicher-intelligenz/mit-ki-gegen-viren-wie-neue-technologien-die-impfstoffforschung-voranbringen/

Mit KI gegen Viren: Wie neue Technologien die Impfstoffforschung voranbringen

Wissenschaftler nutzen Künstliche Intelligenz, um Proteinstrukturen von Viren zu entschlüsseln - Grundlage für zukünftige Impfstoffe.

Tino Eberl
Very interesting article on #DengueVirus #ReplicationComplex
Structures of dengue virus RNA replicase complexes: Molecular Cell
https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00470-7
#polymerase #CryoEM #flaviviridae
“Dengue Virus Evolution in India: Urgent Need for Vaccine Highlighted by Researchers” - mindvoice

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mindvoice - the news from healthy mind

Japanese Encephalitis Virus is a Mosquitoborne Flaviviridae which puts it in the same group as the classical Viral Haemorrhagic Fevers (Dengue, Yellow Fever, debatabley Zika [Zika is a Flavivirus, though it is debatable whether it is a Classical Viral Haemorrhagic Fever or even a Viral Haemorrhagic Fever since the most haemorrhagic symptom one might experience is a little blood in the urine, or blood in semen, it is more neurological]) and various Mosquitoborne Encephalitises.

Japanese encephalitis and the new vaccine recommendations ― Outbreak News TV

#Virology #Flaviviridae

I find it incredibly weird that some tend to include the Paramyxoviridae (Parainfluenza) family, genus henipavirus in the category of Viral Haemorrhagic Fevers, like yes Hendra henipavirus and Nipah henipavirus both are slightly more lethal than Ebolaviruses and Marburgviruses but if anyone is going to haemorrhage during Hendra Virus Disease (the film Contagion bases its virus on this one) it is going to be into the lungs, and the primary threat is fulminant encephalomeningitis or kidney failure, it isn't systemically haemorrhagic like the classical (Dengue, Yellow fever, mainly Flaviviridae) and severe (Ebola, Marburg, Lassa) VHFs.

#Virology #SevereViralDiseases #ViralHaemorrhagicFevers #HendraHenipavirus #NipahHenipavirus #Ebolaviruses #Marburgviruses #Filoviridae #Paramyxoviridae #Henipaviruses #Flaviviridae #LassaArennavirus