Egon Willighagen#SWAT4HCLS is over.
Today, I am at the #KNCV CTC meeting, where we are launching the #Cheminformatics and #DrugDiscovery working group, as part of the CTC Section
Stephan HackerHe also hinted at a new class of synthetic antibiotics that is in current development at Roche. Hopefully there are many more new antibiotics in the future. (7/7)
#Antibiotics #DrugDiscovery #DrugDevelopment #ChemBio #Chemistry #cryoEM #AMR #Resistance #Bacteria #SAR #Synthesis #Zosurabalpin
Stephan HackerHe also hinted at a new class of synthetic antibiotics that is in current development at Roche. Hopefully there are many more new antibiotics in the future. (8/8)
#Antibiotics #DrugDiscovery #DrugDevelopment #ChemBio #Chemistry #cryoEM #AMR #Resistance #Bacteria #SAR #Synthesis #Zosurabalpin
LED3hubWe are very happy that Thomas Clairfeuille from Roche visited us today for a very well attended LED3 Lecture. He talked about "The discovery and mechanism of lipid transport inhibition by the antibiotic Zosurabalpin".
https://www.nature.com/articles/s41586-023-06873-0
#Antibiotics #DrugDiscovery #ChemBio #Chemistry
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CSBJπ¦ Could algorithms help us outpace evolving superbugs?
π Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0008
π CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#AntibioticResistance #DrugDiscovery #ComputationalBiology #StructuralBiology #MachineLearning #Bioinformatics
𧱠What if activation and inhibition are not about binding but about motion?
π Antagonist Binding Actively Disrupts Interleukin-1 Receptor Dynamics to Block Co-receptor Recruitment. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0017
π CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
#DrugDiscovery #Immunology #ProteinDynamics #Inflammation #Biophysics #StructuralBiology #ComputationalBiology #Cytokines
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SELFRIDGES CoBack in the day (but not as far back as Quaalude days) when you went to the Oakland office to apply for an ABC license there was this cute display of illegal drugs in the waiting area. Now you canβt find ludes and I think you have to go to Concord to apply. #stoner #cannabiseducation #Cannabissamen #drugdiscovery #stonerrock #fyp #fypγ· #710AM #420everyday #420allday #420at0300
#KNCVMCCB2026 comes to an end with an interesting talk by Danielle Vugts. She talked about the importance of #imaging during #DrugDevelopment on the example of PET imaging of #biologics.
https://link.springer.com/article/10.1186/s41181-024-00258-y
#DrugDiscovery #PETImaging #Radiolabeling #Antibodies #Nanoparticles #Chemistry
