OpenAI (@OpenAI) on X

To go deeper on our new Life Sciences model series, research lead @joyjiao12 and product lead Yunyun Wang joined @AndrewMayne on the OpenAI Podcast to discuss how we’re building models for biology, drug discovery, and translational medicine. They cover both the opportunity and

PUBLIC MLCB Postdoctoral Research at Broad Institute current

Postdoctoral position: machine learning for drug discovery Purdue University, West Lafayette, Indiana Discover causes and cures for disease through research in the Carpenter–Shen laboratory! Want to devote your expertise in data science to accelerate the pace at which new medicines are found...

OpenAI (@OpenAI) on X

Introducing GPT-Rosalind, our frontier reasoning model built to support research across biology, drug discovery, and translational medicine.

OpenAI (@OpenAI) on X

To go deeper on our new Life Sciences model series, research lead @joyjiao12 and product lead Yunyun Wang joined @AndrewMayne on the OpenAI Podcast to discuss how we’re building models for biology, drug discovery, and translational medicine. They cover both the opportunity and

Tropical psychotria plants are a rich source for peptide inhibitors of human prolyl oligopeptidase - Natural Products and Bioprospecting

Peptides from natural sources have often served as valuable leads in drug discovery. Plant-derived protease inhibitors are a notable class, yet their distribution, diversity, and targets remain underexplored. Here, eleven tropical Psychotria species were screened for cyclic cysteine-rich peptides, with extracts showing concentration-dependent inhibition of human prolyl oligopeptidase (POP). Peptidomics combining mass spectrometry and transcriptome mining revealed multiple inhibitory peptides. From Psychotria solitudinum, which contained 37 peptides, a novel peptide (psysol 3) was purified and sequenced. Its synthetic analogue inhibited POP with an IC50 of ~ 1.3 µM. Sequence analysis and synthetic probes identified loop 3 as the inhibitory motif. Psysol 3 is a new probe for POP pharmacology and future structure–activity studies.

Webinar Registration "AI for Molecular Discovery: From Drug Design to Protein Dynamics" - CA Viral Targets ANRS MIE

Artificial intelligence and biology: AI’s potential for launching a novel era for health and medicine | The-14

AI is transforming biology and medicine, enabling faster discoveries and treatments, but challenges in data, ethics, and causality remain significant today.