Waka/Joewaka
Howard Smith MD, AMEmpowering Ovarian Cancer Immunotherapy. Aggressive ovarian cancers are deadly because they block a patient’s immune system. A new study demonstrates how this shield can be removed. #OvarianCancer #CancerResearch #Immunotherapy #MedicalBreakthrough #FutureMedicine
https://www.instagram.com/p/DW4hROxj-EJ/
Howard G. Smith MD, AM on Instagram: "Empowering Ovarian Cancer Immunotherapy Aggressive ovarian cancers are deadly in part because they block a patient’s immune system from recognizing the tumor. This is why immunotherapy frequently fails. A new study suggests scientists may have found a way to remove that shield. UC-San Diego oncologists discover that many ovarian tumors produce high levels of a protein called FAK, focal adhesion kinase, which helps cancer cells hide from immune killer cells. When the researchers block FAK protein production and add chemotherapy in animal studies, an important synergy develops: • More immune T cells and B cells converge on the tumor. • Tumor growth slows. • Survival improves. Even more interesting, blocking FAK reprograms immune macrophages so they begin sending signals that recruit other immune cells to attack the tumor. The bottom line: if randomized clinical studies confirm that combining effective chemotherapy with FAK inhibitors that energize immunotherapy creates a more powerful strategy against advanced ovarian cancer, we could see more women successfully fighting this deadly cancer….someday soon. #OvarianCancer #CancerResearch #Immunotherapy #MedicalBreakthrough #FutureMedicine"
0 likes, 0 comments - drhowardsmithreports on April 8, 2026: "Empowering Ovarian Cancer Immunotherapy Aggressive ovarian cancers are deadly in part because they block a patient’s immune system from recognizing the tumor. This is why immunotherapy frequently fails. A new study suggests scientists may have found a way to remove that shield. UC-San Diego oncologists discover that many ovarian tumors produce high levels of a protein called FAK, focal adhesion kinase, which helps cancer cells hide from immune killer cells. When the researchers block FAK protein production and add chemotherapy in animal studies, an important synergy develops: • More immune T cells and B cells converge on the tumor. • Tumor growth slows. • Survival improves. Even more interesting, blocking FAK reprograms immune macrophages so they begin sending signals that recruit other immune cells to attack the tumor. The bottom line: if randomized clinical studies confirm that combining effective chemotherapy with FAK inhibitors that energize immunotherapy creates a more powerful strategy against advanced ovarian cancer, we could see more women successfully fighting this deadly cancer….someday soon. #OvarianCancer #CancerResearch #Immunotherapy #MedicalBreakthrough #FutureMedicine".
Your Morning Cup of Joe Could Help Fight Cancer. A gene-editing system, switched on by the caffeine in coffee, chocolate, or cola soda, could one day activate powerful therapies against cancer or diabetes. #CoffeeScience #CRISPR #CancerResearch #FutureMedicine #HealthInnovation
https://www.instagram.com/p/DW4dSS3lOUk/
https://www.instagram.com/p/DW4dSS3lOUk/
Howard G. Smith MD, AM on Instagram: "Your Morning Cup of Joe Could Help Fight Cancer A gene-editing system, switched on by the caffeine in coffee, chocolate, or cola soda, could one day activate powerful therapies against cancer or diabetes. Cancer and translational medicine biologists at Texas A&M engineered cells so that about 20 mg of caffeine, roughly that in a small sip of coffee, triggers a molecular “on switch.” When caffeine is present, specially designed molecules the investigators have termed “caffebodies” join together and activate CRISPR gene editing inside cells. Instead of drugs constantly affecting your body’s organs and tissues, doctors could turn gene therapies on only when needed. For example, immune T-cells could be programmed to attack tumors when activated by consuming caffeine. To fine tune the control, the researchers developed a stop switch using a medication called rapamycin. This agent turns off the gene editing a promises to provide a precise control over treatment. This caffeine-controlled advanced gene therapy system promises to have applications beyond cancer treatment. Sips of coffee or doses of rapamycin could be employed by diabetics to turn on and off insulin production. Though clinical application is far off in the future, this work is an exciting proof-of-concept. References On My Website. #CoffeeScience #CRISPR #CancerResearch #FutureMedicine #HealthInnovation"
0 likes, 0 comments - drhowardsmithreports on April 8, 2026: "Your Morning Cup of Joe Could Help Fight Cancer A gene-editing system, switched on by the caffeine in coffee, chocolate, or cola soda, could one day activate powerful therapies against cancer or diabetes. Cancer and translational medicine biologists at Texas A&M engineered cells so that about 20 mg of caffeine, roughly that in a small sip of coffee, triggers a molecular “on switch.” When caffeine is present, specially designed molecules the investigators have termed “caffebodies” join together and activate CRISPR gene editing inside cells. Instead of drugs constantly affecting your body’s organs and tissues, doctors could turn gene therapies on only when needed. For example, immune T-cells could be programmed to attack tumors when activated by consuming caffeine. To fine tune the control, the researchers developed a stop switch using a medication called rapamycin. This agent turns off the gene editing a promises to provide a precise control over treatment. This caffeine-controlled advanced gene therapy system promises to have applications beyond cancer treatment. Sips of coffee or doses of rapamycin could be employed by diabetics to turn on and off insulin production. Though clinical application is far off in the future, this work is an exciting proof-of-concept. References On My Website. #CoffeeScience #CRISPR #CancerResearch #FutureMedicine #HealthInnovation".
The-14Treating previously untreatable cancers: How CAR‑T cell therapy could be made accessible to more patients
#Canada #Health #CancerTreatment #CARTCellTherapy #MedicalInnovation #Biotech #CancerResearch #Medicine #AccessToCare #ClinicalTrials #Science
https://the-14.com/treating-previously-untreatable-cancers-how-car-t-cell-therapy-could-be-made-accessible-to-more-patients/
#Canada #Health #CancerTreatment #CARTCellTherapy #MedicalInnovation #Biotech #CancerResearch #Medicine #AccessToCare #ClinicalTrials #Science
https://the-14.com/treating-previously-untreatable-cancers-how-car-t-cell-therapy-could-be-made-accessible-to-more-patients/
Broermann AwardToday, on World Health Day, we celebrate our 2025 BMIA Laureates, Prof. June and Prof. Sadelain, and their groundbreaking innovation: CAR-T cell therapy!
This year’s theme, “Together for health. Stand with science”, highlights exactly what their work represents –how collaboration and scientific excellence can transform patient care and save lives.
#WorldHealthDay #StandWithScience #MedicalInnovation #CARTCellTherapy #BMIA #Healthcare #Research
#cancer #cancerresearch #cancercure
Dr. Interested
Knowable MagazineBetter outcomes may come from new drugs, strategies to rev up the immune system and learning to identify the disease sooner in its course — here's how scientists are making progress fighting pancreatic cancer 👇
https://knowablemagazine.org/content/article/health-disease/2025/progress-for-pancreatic-cancer
NewsletterTFPancreatic Cancer: A Looming Shadow or Shifting Sands?
Are new weight loss drugs causing pancreatic cancer? Experts look at smoking and other factors. What you need to know.
#PancreaticCancer, #WeightLossDrugs, #SmokingRisks, #HealthNews, #CancerResearch
https://newsletter.tf/weight-loss-drugs-pancreatic-cancer-risk-smoking/
Concerns are rising about pancreatic cancer, with some looking at new weight loss drugs, but smoking is still a major cause.
#PancreaticCancer, #WeightLossDrugs, #SmokingRisks, #HealthNews, #CancerResearch
https://newsletter.tf/weight-loss-drugs-pancreatic-cancer-risk-smoking/
Dr Joe PajakReports that a new Australian review finds vaping may raise cancer risk, highlighting uncertainties around long‑term health effects.
More research is underway to clarify the dangers.
Source: Lauren Roberts, https://www.abc.net.au/
#Vaping
https://www.abc.net.au/news/health/2026-03-31/vaping-cancer-likely-to-cause-cancer-australian-research/106503804 #HealthNews #CancerResearch
More research is underway to clarify the dangers.
Source: Lauren Roberts, https://www.abc.net.au/
#Vaping
https://www.abc.net.au/news/health/2026-03-31/vaping-cancer-likely-to-cause-cancer-australian-research/106503804 #HealthNews #CancerResearch
