Mediterranean diet with lean beef shows no spike in heart-risk indicator: Study
A new analysis out of Penn State is pushing back on the long-standing belief that beef automatically spells trouble for the heart. The researc…
#dining #cooking #diet #food #mediterranean #MediterraneanDiet #MediterraneanFood #Beef #cardiovasculardisease #hearthealth #LeanBeef #Mediterranean #TMAO
https://www.diningandcooking.com/2389030/mediterranean-diet-with-lean-beef-shows-no-spike-in-heart-risk-indicator-study/
Mediterranean diet with lean beef shows no spike in heart-risk indicator: Study
A new analysis out of Penn State is pushing back on the long-standing belief that beef automatically spells trouble for the heart. The research team, writing in the Journal of …
#dining #cooking #diet #food #MediterraneanDiet #Beef #cardiovasculardisease #hearthealth #LeanBeef #Mediterranean #TMAO
https://www.diningandcooking.com/2389030/mediterranean-diet-with-lean-beef-shows-no-spike-in-heart-risk-indicator-study/
⚠️ Choline: Essential or a hidden risk?
A new study links 100mg/day of choline to a +6% increase in all-cause mortality and +11% in heart-related deaths.
But what does the science really say?
In this video, we break down:
🧬 How choline converts into TMAO
📉 The surprising betaine & stroke connection
✅ Why panic isn’t the answer—and how to stay balanced
🎥 Watch now and make sense of the headlines:
👉 https://www.youtube.com/watch?v=0uubYweHpks&list=PLCFAL8lW1qRcyFIOikD6P0TkXz8YNQBKT&index=1&t=27s
#Choline #TMAO #MortalityRisk #HeartHealth #NutritionScience
0 likes, 0 comments - drhowardsmithreports on February 12, 2025: "Meaty Treats Could Lead To Dementia Regularly consuming hot dogs and bacon could increase your chances of developing dementia by 13%. Eating those steaks consistently leads to a 16% higher risk of cognitive decline. A new study by researchers from Mass General Brigham and the Harvard School of Public Health followed more than 133,000 (133,771) individuals for up to 43 years. As few as two slices of bacon consumed regularly accelerates your cognitive aging by 1.6 years and triggers a cognitive decline that is an early marker of dementia. Why? Saturated fats, salt, and a gut-derived compound called TMAO, trimethylamine N-oxide, are the brain-damaging culprits. The good news. Substituting fish, nuts, or legumes for the franks, bacon, and t-bones could reduce your dementia risk by 19%. https://www.massgeneralbrigham.org/en/about/newsroom/press-releases/red-meat-increases-risk-of-dementia https://www.neurology.org/doi/10.1212/WNL.0000000000210286 #dementia #redmeat #bacon #hotdogs #tmao".
I have MCAS and my daughter has ME symptoms. My daughter and I both take ALCAR and in order to avoid getting a choline depletion headache I also take citicoline (aka CDP-choline). I don't give my daughter citicoline since she eats ~ 4 whole eggs a week and also eats beans (I can't eat either). I've been thinking about giving her the supplement, though. I had been a bit concerned about TMAO, but I'm thinking the TMAO story is probably a red herring.*
* Microbial trimethylamine-N-oxide as a disease marker: something fishy?
https://doi.org/10.1080/16512235.2017.1327309
Trimethylamine N-Oxide in Relation to Cardiometabolic Health—Cause or Effect?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284902/
Deligthed to see this work out, from Petros Andrikopoulos, demonstrating the TMAO-cardiometabolomic health story is complicated. #Microbiome #TMAO #cardiometabolism
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide https://www.nature.com/articles/s41467-023-39824-4
TMAO is known to be atherothrombotic. Here the authors show that i) kidney function is the main determinant of serum TMAO, ii) TMAO increases kidney scarring with TGF-β1 signalling and iii) anti-diabetic drugs with reno-protective properties such as GLP1R agonists reduce plasma TMAO.
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide with implications for heart and kidney disorders https://www.medrxiv.org/content/10.1101/2022.11.08.22282073v1
Preprint from the EU Metacardis study (1741 adults) showing that increasing circulating serum fasting levels of #TMAO are associated with 1) increasing age and 2) reduced kidney function. #Microbiota and #diet play minor roles. Context: metabolic health more important.
Mediterranean Diet
Dining and Cooking
Dr. Lukas Morcinek
Howard Smith MD, AM
Rhyothemis
Professor Lesley Hoyles