What if we could precisely track a single #virus particle as it is moving around in the #extracellular space at the millisecond timescale?

Researchers at Duke University have developed a fascinating new technique called 3D tracking and #imaging (3D-TrIm).

Research article in Nature Methods: https://www.nature.com/articles/s41592-022-01672-3

Web page of the Welsher lab: https://www.welsherlab.org/3d-trim-captures-viral-first-contacts/

Video source: YouTube

#microscopy #singleparticletracking #infection

Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking - Nature Methods

3D-TrIm combines real-time, high-speed, single-virion tracking with volumetric imaging of cellular microenvironments.

Nature

#introduction

Hi fellow humans, I am Laura (zie/zir if possible, otherwise she/her), a senior staff scientist at #LSFOctopus advanced #LightMicroscopy and #CLEM facility at #HarwellCampus in the #UK, right next to #DiamondLightSource.

My science interest center around #EGFRSignalling and #RTKSignalling and deregulation in #CancerStudies in general. My tools of the trade are #singleparticletracking #singlemoleculelocalisation #CLEM #FIBSEM #VolumeEM and #CryoMicroscopy

HMU for science chat

Hi #science mastodon! My work boils down to this question: Is membrane-proximal #actin generating #diffusion barriers for #membrane molecules?

I am a PhD student of Helge Ewers at FU Berlin. I work in #neurons because actin forms very well-behaved rings there. My approach is combining #SingleParticleTracking of membrane proteins and #SuperResolution #microscopy of the #cytoskeleton via #STORM and #STED. Lots of #biophysics , #CellBiology and #neuroscience. #introduction #ScienceMastodon