Does molecular dynamics improve RNA models? This short video presents key findings from our latest paper. We asked when and why molecular dynamics helps (or fails to help) refine RNA structures. In this work, we share practical guidelines on how to use MD as a diagnostic tool, not a universal fixer.
Full paper: https://doi.org/10.1016/j.csbj.2025.10.003
#RNA #ComputationalBiology #Bioinformatics #RNAstructure #MolecularDynamics #CASP
RNA structure prediction is hard. How much does that matter?

4.8k words, 22 minute reading time

Owl Posting

A quantitative framework for structural interpretation of DMS reactivity.

#SHAPE #DMSO #RNAstructure #Preprint

https://www.biorxiv.org/content/10.1101/2024.11.21.624766v1

We have a #PhD available!! Are you interested in #cryoEM 🔬and #RNAstructure🧬? Then this might be for you: tinyurl.com/4uecm38r It's a 4-year funded position through @BBSRCWhiteRose; DM or email me for more details. #RNA #CryoEM #molecularbio #generegulation #Structbio #structuralbiology