Arjan BoltjesKick-off of the #scNL annual meeting starting now, hosted in the #PrincessMaximaCenter
Good show up, decently filled auditorium.
Program: https://www.singlecell.nl/events/annual-meeting-2024
"Integrative analysis of #neuroblastoma by single-cell RNA sequencing identifies the #NECTIN2-#TIGIT axis as a target for #immunotherapy"
https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00436-1
Great new work from Judith Wienke et al. from the Molenaar lab in the #PrincessMaximaCenter in #Utrecht.
Great to see this out after seeing it in our group meetings several times. In vivo results sometimes are impressive, but very much in a subgroup it seems. Intriguiging, and curious what underlies this.
"Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma"
Nice new work based on #scRNAseq from our Drost group colleagues at the #PrincessMaximaCenter. a.o., a potential role of #NECTIN3 and #TIGIT in #tumour-induced T cell dysfunction.
https://www.nature.com/articles/s41467-023-38886-8
Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma - Nature Communications
The cellular differentiation states of paediatric rhabdomyosarcoma (RMS) remain to be explored. Here, single-cell RNA sequencing analysis of RMS tumours reveals an immunosuppressive microenvironment and distinct transcriptional programs predictive of patient outcomes.
Early at the #PrincessMaximaCenter, sun ☀️ is out, #scRNAseq analysis running, pot of #tea, and this #BandcampDaily playing: https://daily.bandcamp.com/features/music-in-exile-mashhad-2022-interview
I'm at the second album now - great start of the day. ❤️
