Dr Syd (@sydmj.bsky.social)
Poverty CAN harm development, but your OP implies it WILL, which will be used as an excuse to write off kids who grow up poor. Is it wrong that kids grow up in poverty? It 100% is. Should we do something about it? We should. But the brains of poor kids can also be ok.
Human molecular map contributes to understanding of disease mechanisms
https://www.sciencedaily.com/releases/2024/09/240911175947.htm
Roadmap to molecular human linking multiomics w. population traits, diabetes subtype
https://www.nature.com/articles/s41467-024-51134-x
6,304 quantitative molec. traits
1,221,345 genetic variants
methylation @ 470,837 DNA CpG sites
gene expression: 57,000 transcripts
#metabolome #connectome #interactome #genotype #phenotype #IndividualVariation #transcriptome #multiomics #omics #disease #MolecularEpidemiology #GeneExpression
Human 'molecular map' contributes to the understanding of disease mechanisms
Scientists have created an intricate molecular map of the human body and its complex physiological processes based on the analysis of thousands of molecules in blood, urine and saliva samples from 391 volunteers. The data was integrated to create a powerful, interactive visual web-based tool called Connecting Omics (COmics) that can be used to investigate the complex molecular make-up of humans and discover underlying traits associated with various diseases.
Mouse spontaneous #behavior reflects #IndividualVariation rather than #estrous state
#OpenAccess
"These findings suggest underlying functional #stability to the circuits that support exploration in female mice, reveal a surprising degree of specificity in individual behavior, and provide empirical support for the #inclusion of both #sexes in #experiments querying spontaneous behaviors"
https://www.cell.com/current-biology/fulltext/S0960-9822(23)00175-6
Mouse spontaneous behavior reflects individual variation rather than estrous state
Levy et al. track open-field behavior of female mice over weeks and find that behavior
reflects individual identity far more than estrous state. Open-field exploration patterns
in males are much more variable than in females, arguing for the inclusion of both
sexes in studies of spontaneous behaviors.
Allen Tien, MD, MHS mdlogix.com 94,698 田一彦
Victoria Stuart 🇨🇦 🏳️⚧️
Christophe Bousquet