Farmed #fur #animals harbour #viruses with #zoonotic #spillover potential, Nature: https://www.nature.com/articles/s41586-024-07901-3
We identified 7 species of #coronaviruses, expanding their known host range, & documented cross-species transmission of a novel #canine respiratory coronavirus to raccoon dogs & of #bat HKU5-like CoV to #mink, present at a high abundance in lung tissues. 3 subtypes of #influenza A virus—#H1N2, #H5N6 & #H6N2—were detected in #lungs of guinea pig, mink and #muskrat, respectively.
Major #change in #swine #influenza virus diversity in #France owing to emergence and widespread #dissemination of a newly introduced #H1N2 1C genotype in 2020 http://biorxiv.org/cgi/content/short/2024.07.25.605108v1?rss=1
It was characterized by an HA-1C.2.4, an N2-Gent/84, and internal protein-encoding genes belonging to a newly defined genogroup within the #Eurasian avian-like (EA) #lineage, the EA-DK subclade.
The #evolution, #complexity, and #diversity of swine #influenza viruses in #China: A hidden public #health #threat, Virology: https://www.sciencedirect.com/science/article/abs/pii/S0042682224001880?via%3Dihub
G4 and G5 reassortant EA #H1N1 viruses are the most prevalent in Chinese #pig herds. Clade 6B.1 pdm/09H1N1 viruses were found to be transmitted from humans to pigs. Three new #H1N2 #genotypes were identified using the genomic backbones of G4 or G5 viruses.
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[4] Mallapaty, S., 2024. Bird flu could become a human pandemic - How are countries preparing? Nature d41586-024-02237-4+. https://doi.org/10.1038/d41586-024-02237-4
(archived: https://web.archive.org/web/20240713112408/https://www.nature.com/articles/d41586-024-02237-4 )
Cited #preprints on spreading "through contaminated milking equipment"
- Caserta, L.C., et al., 2024. https://doi.org/10.1101/2024.05.22.595317
- Another ref. seems to have issues
Le Sage, V. et al., 2024 - which in bioRxiv can only be https://doi.org/10.1101/2024.01.05.574401
(but its main topic is #swine #H1N2 influenza viruses)
Potential #pandemic #risk of circulating swine #H1N2 #influenza viruses, Nat Commun.: https://www.nature.com/articles/s41467-024-49117-z
These results indicate that this α-swH1N2 strain has a higher pandemic potential, but a moderate level of #impact since there is reduced #replication #fitness and #pathology in animals with prior #immunity.
Influenza A viruses pose a continuing pandemic threat to humans. Le Sage, et al. describe a pandemic triage pipeline to evaluate the pandemic risk of emerging viruses and utilize it to characterize two widespread swine influenza A viruses.
Large-Scale #Serological #Survey of #Influenza A Virus in South #Korean Wild #Boar (Sus scrofa) https://pubmed.ncbi.nlm.nih.gov/38842623/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1fgJURi2yzLesFml6et0Bb6krzs_FrNIYgPYVFN50JPwVNFg9s&fc=None&ff=20240606155644&v=2.18.0.post9+e462414
Detected subtypes included 23 cases of pandemic 2009 #H1N1, six of human seasonal #H3N2, three of classical swine H1N1, 13 of triple-reassortant swine #H1N2, seven of triple-reassortant swine H3N2, and seven of swine-origin H3N2 variant. Notably, none of the serum samples tested positive for avian IAV subtypes #H3N8, #H5N3, #H7N7, and #H9N2 or canine IAV subtype H3N2.
In this comprehensive large-scale study, conducted from 2015 to 2019, 7,209 wild boars across South Korea were sampled to assess their exposure to influenza A viruses (IAVs). Of these, 250 (3.5%) were found to be IAV-positive by ELISA, and 150 (2.1%) by the hemagglutination inhibition test. Detected …
#Influenza at the #human - #animal #interface #summary and #assessment, 3 May 2024, #WHO: https://www.who.int/publications/m/item/influenza-at-the-human-animal-interface-summary-and-assessment-3-may-2024
Overview: From 29 March to 3 May 2024, one human case of #infection with an influenza A(#H5N1) virus, one human case of infection with an A(#H9N2) virus, one human case of infection with an influenza A(#H10N3) virus and one human case of infection with an influenza A(#H1N2) variant virus were reported officially.
#US #CDC Reports First U.S. #Human #Infection in 2024 with #Variant #Influenza #H1N2 Virus, https://www.cdc.gov/flu/spotlights/2023-2024/first_us_human_infection_avian_flu.htm
The infection with an influenza A(H1N2) variant (v) virus occurred in a #child living near a #pig #farm in #Pennsylvania who had direct contact with pigs prior to illness onset. The person was hospitalized and has since recovered from their illness.
#USA, One #human #infection with an #influenza A #H1N2 #variant virus was reported by the #Pennsylvania Department of Health. CDC: https://www.cdc.gov/flu/weekly/index.htm
The patient is < 18 years of age, sought healthcare during the week ending March 9, 2024 (week 10), was hospitalized, and has since recovered. An investigation by local public health officials found that the patient had swine contact prior to their illness onset.